KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARCKSL1
All Species:
17.88
Human Site:
S48
Identified Species:
43.7
UniProt:
P49006
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49006
NP_075385.1
195
19529
S48
S
P
K
G
E
G
E
S
P
P
V
N
G
T
D
Chimpanzee
Pan troglodytes
XP_001151702
325
32808
S178
S
P
K
G
E
G
E
S
P
P
V
N
G
T
D
Rhesus Macaque
Macaca mulatta
XP_001082393
330
31424
A74
A
D
K
E
E
P
A
A
A
G
S
G
A
A
S
Dog
Lupus familis
XP_854637
199
19796
S48
S
P
K
G
E
G
E
S
P
P
V
N
G
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P28667
200
20147
S48
T
P
K
G
E
G
E
S
P
P
V
N
G
T
D
Rat
Rattus norvegicus
Q9EPH2
199
19829
S48
T
P
K
G
E
G
E
S
P
P
V
N
G
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520379
114
11763
Chicken
Gallus gallus
P16527
281
27710
G52
S
P
A
A
A
E
A
G
K
E
E
V
Q
A
N
Frog
Xenopus laevis
NP_001108274
193
20338
N46
N
G
E
A
A
P
T
N
G
S
A
E
P
P
A
Zebra Danio
Brachydanio rerio
NP_001015060
227
23228
E71
K
A
E
E
G
K
A
E
E
G
D
A
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
37.8
92.9
N.A.
94
92.4
N.A.
39.4
40.5
31.2
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.3
43.9
94.4
N.A.
95.5
93.4
N.A.
44
49.1
46.1
52.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
93.3
86.6
N.A.
0
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
93.3
N.A.
0
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
20
20
0
30
10
10
0
10
10
10
30
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
40
% D
% Glu:
0
0
20
20
60
10
50
10
10
10
10
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
50
10
50
0
10
10
20
0
10
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
60
0
0
10
0
0
10
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
50
0
0
10
% N
% Pro:
0
60
0
0
0
20
0
0
50
50
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
40
0
0
0
0
0
0
50
0
10
10
0
0
0
10
% S
% Thr:
20
0
0
0
0
0
10
0
0
0
0
0
0
40
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
50
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _