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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
30.91
Human Site:
T377
Identified Species:
45.33
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
T377
R
V
R
H
I
S
P
T
A
P
D
T
L
G
C
Chimpanzee
Pan troglodytes
XP_528027
455
49608
E363
S
S
M
E
D
H
L
E
I
L
E
W
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
T377
R
V
R
H
I
S
P
T
A
P
D
T
L
G
C
Dog
Lupus familis
XP_539802
469
51364
T377
R
I
R
H
I
S
P
T
A
P
D
T
L
G
C
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
T377
R
V
R
H
I
S
P
T
A
P
D
T
L
G
C
Rat
Rattus norvegicus
Q6AXY4
469
51328
T377
R
V
R
H
I
S
P
T
A
P
D
T
L
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
T377
R
V
G
H
I
S
P
T
A
P
D
T
L
G
C
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
T377
Q
V
G
H
L
C
P
T
A
P
D
T
L
G
C
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
T375
R
L
R
H
L
A
P
T
A
P
D
T
L
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
V348
C
T
L
T
W
G
H
V
A
P
T
A
P
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
W367
A
I
E
N
I
I
K
W
Q
H
V
A
P
N
C
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
P359
L
K
Y
G
H
I
A
P
S
A
P
D
T
L
A
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
A359
T
L
K
W
R
H
L
A
P
T
A
P
N
T
L
Maize
Zea mays
NP_001168398
435
48508
A352
T
L
R
W
R
H
L
A
P
T
A
P
N
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
P373
L
R
W
R
H
L
A
P
T
A
P
N
T
L
G
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
R395
F
K
D
D
I
E
H
R
L
D
L
M
E
C
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
93.3
N.A.
73.3
80
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
100
N.A.
13.3
N.A.
26.6
6.6
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
0
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
13.3
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
13
13
57
13
13
13
0
0
7
% A
% Cys:
7
0
0
0
0
7
0
0
0
0
0
0
0
7
57
% C
% Asp:
0
0
7
7
7
0
0
0
0
7
50
7
0
7
0
% D
% Glu:
0
0
7
7
0
7
0
7
0
0
7
0
7
0
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
7
0
7
0
0
0
0
0
0
0
50
7
% G
% His:
0
0
0
50
13
19
13
0
0
7
0
0
0
0
0
% H
% Ile:
0
13
0
0
50
13
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
13
7
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
13
19
7
0
13
7
19
0
7
7
7
0
50
19
13
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
7
13
7
0
% N
% Pro:
0
0
0
0
0
0
50
13
13
57
13
13
13
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
44
7
44
7
13
0
0
7
0
0
0
0
0
0
7
% R
% Ser:
7
7
0
0
0
38
0
0
7
0
0
0
0
7
0
% S
% Thr:
13
7
0
7
0
0
0
50
7
13
7
50
19
7
13
% T
% Val:
0
38
0
0
0
0
0
7
0
0
7
0
0
0
0
% V
% Trp:
0
0
7
13
7
0
0
7
0
0
0
7
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _