Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLD2 All Species: 28.79
Human Site: T305 Identified Species: 42.22
UniProt: P49005 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49005 NP_001120690.1 469 51289 T305 E F D P T N Y T L P Q Q P L H
Chimpanzee Pan troglodytes XP_528027 455 49608 P291 L Q L S A S V P V D V M P G E
Rhesus Macaque Macaca mulatta XP_001093710 469 51277 T305 E F D P T N Y T L P Q Q P L H
Dog Lupus familis XP_539802 469 51364 T305 E F D P T N Y T L P Q Q P L H
Cat Felis silvestris
Mouse Mus musculus O35654 469 51350 T305 E F D P T N Y T L P Q Q P L H
Rat Rattus norvegicus Q6AXY4 469 51328 T305 E F D P T N Y T L P Q Q P L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520117 471 51420 T305 E F D P T N F T L P Q Q P L H
Chicken Gallus gallus
Frog Xenopus laevis O93610 463 50629 I305 A F D P T N Y I L P Q Q P L H
Zebra Danio Brachydanio rerio NP_998468 467 51808 T303 Q Y D P T N Y T L P Q Q P L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W088 431 47990 A276 M P G P Y D P A N F M L P Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19366 451 50385 D295 D V T P G V G D P C S S M W P
Sea Urchin Strong. purpuratus XP_782368 442 49455 S287 G D F D P A N S S L P Q Q P F
Poplar Tree Populus trichocarpa XP_002309305 442 49175 N287 P G S N D P A N F A L P Q Q P
Maize Zea mays NP_001168398 435 48508 N280 P G C H D P A N F S L P Q Q P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48520 456 51321 F301 G T N D P A N F A L P Q Q P L
Baker's Yeast Sacchar. cerevisiae P46957 487 55277 S323 H K S L F D K S L E S Y F N G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 98.9 93.1 N.A. 94.2 94 N.A. 85.3 N.A. 68.8 66.5 N.A. 40 N.A. 28.3 50.5
Protein Similarity: 100 97 99.5 96.5 N.A. 97 96.8 N.A. 90.8 N.A. 79 79.7 N.A. 56.5 N.A. 50.1 66.3
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 N.A. 86.6 100 N.A. 20 N.A. 13.3 13.3
Percent
Protein Identity: 41.5 38.8 N.A. 39.6 25.4 N.A.
Protein Similarity: 56.9 56.9 N.A. 57.1 48 N.A.
P-Site Identity: 0 0 N.A. 6.6 6.6 N.A.
P-Site Similarity: 0 0 N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 7 13 13 7 7 7 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 7 7 50 13 13 13 0 7 0 7 0 0 0 0 0 % D
% Glu: 38 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % E
% Phe: 0 44 7 0 7 0 7 7 13 7 0 0 7 0 7 % F
% Gly: 13 13 7 0 7 0 7 0 0 0 0 0 0 7 7 % G
% His: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 50 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 7 0 0 0 0 57 13 13 7 0 50 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 7 7 7 0 0 % M
% Asn: 0 0 7 7 0 50 13 13 7 0 0 0 0 7 0 % N
% Pro: 13 7 0 63 13 13 7 7 7 50 13 13 63 13 19 % P
% Gln: 7 7 0 0 0 0 0 0 0 0 50 63 25 19 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 13 7 0 7 0 13 7 7 13 7 0 0 0 % S
% Thr: 0 7 7 0 50 0 0 44 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 0 7 7 0 7 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 7 0 0 7 0 44 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _