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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
22.42
Human Site:
T147
Identified Species:
32.89
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
T147
Q
R
I
K
L
K
G
T
I
D
V
S
K
L
V
Chimpanzee
Pan troglodytes
XP_528027
455
49608
E132
K
Y
I
H
P
D
D
E
L
V
L
E
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
T147
Q
R
I
K
L
K
G
T
I
D
V
S
K
L
V
Dog
Lupus familis
XP_539802
469
51364
S147
Q
R
I
K
L
E
G
S
I
D
A
S
K
L
V
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
T147
Q
R
I
K
L
K
G
T
I
D
V
S
K
L
V
Rat
Rattus norvegicus
Q6AXY4
469
51328
T147
Q
R
I
K
L
K
G
T
I
D
V
S
K
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
T147
Q
R
I
K
L
E
G
T
I
D
V
S
R
L
V
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
A147
Q
R
I
K
L
E
G
A
T
D
V
Q
Q
L
V
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
N145
Q
R
I
K
L
E
G
N
I
D
A
P
K
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
Q119
I
V
L
E
D
E
L
Q
R
V
R
L
Q
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
E138
D
K
Q
T
V
R
L
E
G
N
I
S
M
D
E
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
G130
L
Q
R
V
V
L
T
G
N
I
D
V
Q
T
A
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
K130
E
D
E
S
G
R
V
K
L
G
G
T
V
L
S
Maize
Zea mays
NP_001168398
435
48508
R123
I
L
E
D
E
S
G
R
V
T
L
A
G
A
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
A143
R
V
K
L
A
G
S
A
L
S
P
A
I
Y
V
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
F161
R
V
L
L
V
G
D
F
I
R
S
T
P
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
6.6
100
80
N.A.
100
100
N.A.
86.6
N.A.
66.6
66.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
100
N.A.
100
N.A.
80
73.3
N.A.
26.6
N.A.
40
20
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
33.3
33.3
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
13
0
0
13
13
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
7
7
13
0
0
50
7
0
7
7
0
% D
% Glu:
7
0
13
7
7
32
0
13
0
0
0
7
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
13
0
% F
% Gly:
0
0
0
0
7
13
57
7
7
7
7
0
7
7
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
57
0
0
0
0
0
50
7
7
0
7
0
13
% I
% Lys:
7
7
7
50
0
25
0
7
0
0
0
0
38
0
7
% K
% Leu:
7
7
13
13
50
7
13
0
19
0
13
7
0
50
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
7
7
7
0
0
% P
% Gln:
50
7
7
0
0
0
0
7
0
0
0
7
19
0
0
% Q
% Arg:
13
50
7
0
0
13
0
7
7
7
7
0
7
0
0
% R
% Ser:
0
0
0
7
0
7
7
7
0
7
7
44
0
0
7
% S
% Thr:
0
0
0
7
0
0
7
32
7
7
0
13
0
7
0
% T
% Val:
0
19
0
7
19
0
7
0
7
13
38
7
7
0
57
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _