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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLD2
All Species:
29.7
Human Site:
S257
Identified Species:
43.56
UniProt:
P49005
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49005
NP_001120690.1
469
51289
S257
H
S
T
Q
S
R
D
S
I
N
K
A
K
Y
L
Chimpanzee
Pan troglodytes
XP_528027
455
49608
L243
A
H
V
S
R
V
I
L
A
G
N
L
L
S
H
Rhesus Macaque
Macaca mulatta
XP_001093710
469
51277
S257
H
S
T
Q
S
R
D
S
I
N
K
A
K
Y
L
Dog
Lupus familis
XP_539802
469
51364
S257
H
N
T
Q
S
R
D
S
I
N
K
A
K
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
O35654
469
51350
S257
H
N
T
Q
S
R
D
S
I
N
K
A
K
Y
L
Rat
Rattus norvegicus
Q6AXY4
469
51328
S257
H
N
T
Q
S
R
D
S
I
N
K
A
K
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520117
471
51420
S257
Q
I
T
Q
N
R
D
S
I
T
K
A
K
Y
L
Chicken
Gallus gallus
Frog
Xenopus laevis
O93610
463
50629
S257
E
N
T
Q
G
K
D
S
L
N
K
A
K
Y
L
Zebra Danio
Brachydanio rerio
NP_998468
467
51808
S255
R
S
T
Q
D
K
D
S
T
N
K
A
K
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W088
431
47990
M228
N
S
V
R
A
S
A
M
A
H
V
P
T
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19366
451
50385
V247
T
K
S
N
G
C
D
V
Q
S
V
V
R
T
L
Sea Urchin
Strong. purpuratus
XP_782368
442
49455
G239
S
E
S
T
Q
D
K
G
V
L
T
T
A
K
Y
Poplar Tree
Populus trichocarpa
XP_002309305
442
49175
P239
A
G
N
S
V
E
I
P
S
G
L
L
N
G
Q
Maize
Zea mays
NP_001168398
435
48508
S232
V
G
N
S
V
H
I
S
P
R
F
V
N
G
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48520
456
51321
G253
F
P
R
K
L
I
N
G
Q
V
L
I
T
F
N
Baker's Yeast
Sacchar. cerevisiae
P46957
487
55277
E275
I
K
S
V
N
K
D
E
L
M
I
S
L
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
98.9
93.1
N.A.
94.2
94
N.A.
85.3
N.A.
68.8
66.5
N.A.
40
N.A.
28.3
50.5
Protein Similarity:
100
97
99.5
96.5
N.A.
97
96.8
N.A.
90.8
N.A.
79
79.7
N.A.
56.5
N.A.
50.1
66.3
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
73.3
N.A.
66.6
73.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
80
N.A.
86.6
80
N.A.
33.3
N.A.
33.3
13.3
Percent
Protein Identity:
41.5
38.8
N.A.
39.6
25.4
N.A.
Protein Similarity:
56.9
56.9
N.A.
57.1
48
N.A.
P-Site Identity:
0
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
0
6.6
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
7
0
7
0
13
0
0
50
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
63
0
0
0
0
0
0
0
0
% D
% Glu:
7
7
0
0
0
7
0
7
0
0
0
0
0
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% F
% Gly:
0
13
0
0
13
0
0
13
0
13
0
0
0
13
0
% G
% His:
32
7
0
0
0
7
0
0
0
7
0
0
0
0
7
% H
% Ile:
7
7
0
0
0
7
19
0
38
0
7
7
0
0
0
% I
% Lys:
0
13
0
7
0
19
7
0
0
0
50
0
50
7
0
% K
% Leu:
0
0
0
0
7
0
0
7
13
7
13
13
13
7
57
% L
% Met:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% M
% Asn:
7
25
13
7
13
0
7
0
0
44
7
0
13
0
7
% N
% Pro:
0
7
0
0
0
0
0
7
7
0
0
7
0
0
0
% P
% Gln:
7
0
0
50
7
0
0
0
13
0
0
0
0
0
19
% Q
% Arg:
7
0
7
7
7
38
0
0
0
7
0
0
7
0
0
% R
% Ser:
7
25
19
19
32
7
0
57
7
7
0
7
0
7
0
% S
% Thr:
7
0
50
7
0
0
0
0
7
7
7
7
13
13
0
% T
% Val:
7
0
13
7
13
7
0
7
7
7
13
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _