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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC4A3 All Species: 15.15
Human Site: S224 Identified Species: 41.67
UniProt: P48751 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48751 NP_005061.2 1232 135707 S224 G E K S R P W S P S A S Y D L
Chimpanzee Pan troglodytes XP_516113 1285 141854 S277 G E K S R P W S P S A S Y D L
Rhesus Macaque Macaca mulatta XP_001094457 928 102834 V31 E P P L S P D V E E E D D D L
Dog Lupus familis XP_545662 1162 126740 S209 R E R L C P G S A L G S P G G
Cat Felis silvestris
Mouse Mus musculus P16283 1227 135146 S224 T E K S R P W S P S A S Y D L
Rat Rattus norvegicus P23348 1227 135388 S224 T E K S R P W S P S A S Y D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P15575 922 102205 K25 P E G Y E D T K G S R T S L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920191 1217 137923 T238 R I C I G S M T A M E T A V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791964 1247 140119 E224 E M N P S I R E T M A V H R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.1 75 81.2 N.A. 95.3 95.5 N.A. N.A. 42.5 N.A. 62.7 N.A. N.A. N.A. N.A. 45.1
Protein Similarity: 100 95.4 75.1 83.6 N.A. 96.6 96.6 N.A. N.A. 54.9 N.A. 75.1 N.A. N.A. N.A. N.A. 60.7
P-Site Identity: 100 100 20 26.6 N.A. 93.3 93.3 N.A. N.A. 13.3 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 20 33.3 N.A. 93.3 93.3 N.A. N.A. 20 N.A. 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 23 0 56 0 12 0 0 % A
% Cys: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 12 0 0 0 0 12 12 56 0 % D
% Glu: 23 67 0 0 12 0 0 12 12 12 23 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 23 0 12 0 12 0 12 0 12 0 12 0 0 12 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 12 0 12 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 45 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 23 0 0 0 0 0 12 0 0 0 12 67 % L
% Met: 0 12 0 0 0 0 12 0 0 23 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 12 12 12 12 0 67 0 0 45 0 0 0 12 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 23 0 12 0 45 0 12 0 0 0 12 0 0 12 0 % R
% Ser: 0 0 0 45 23 12 0 56 0 56 0 56 12 0 0 % S
% Thr: 23 0 0 0 0 0 12 12 12 0 0 23 0 0 0 % T
% Val: 0 0 0 0 0 0 0 12 0 0 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 45 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _