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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC4A3
All Species:
4.55
Human Site:
S158
Identified Species:
12.5
UniProt:
P48751
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48751
NP_005061.2
1232
135707
S158
E
P
V
E
P
P
P
S
G
T
P
Q
K
A
K
Chimpanzee
Pan troglodytes
XP_516113
1285
141854
S211
E
P
V
E
P
P
P
S
G
T
P
Q
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001094457
928
102834
Dog
Lupus familis
XP_545662
1162
126740
E143
F
S
I
G
S
D
E
E
D
S
P
G
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P16283
1227
135146
P158
E
P
V
E
P
L
P
P
G
P
P
Q
K
A
K
Rat
Rattus norvegicus
P23348
1227
135388
P158
E
P
V
E
P
P
P
P
G
P
P
Q
K
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P15575
922
102205
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920191
1217
137923
E172
A
T
P
T
E
P
S
E
E
L
P
Q
Y
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791964
1247
140119
N158
K
G
L
H
E
E
A
N
S
K
F
N
E
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
75
81.2
N.A.
95.3
95.5
N.A.
N.A.
42.5
N.A.
62.7
N.A.
N.A.
N.A.
N.A.
45.1
Protein Similarity:
100
95.4
75.1
83.6
N.A.
96.6
96.6
N.A.
N.A.
54.9
N.A.
75.1
N.A.
N.A.
N.A.
N.A.
60.7
P-Site Identity:
100
100
0
6.6
N.A.
80
86.6
N.A.
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
0
26.6
N.A.
80
86.6
N.A.
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
0
0
0
0
0
45
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% D
% Glu:
45
0
0
45
23
12
12
23
12
0
0
0
12
0
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% F
% Gly:
0
12
0
12
0
0
0
0
45
0
0
12
0
0
12
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
12
0
0
45
23
45
% K
% Leu:
0
0
12
0
0
12
0
0
0
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% N
% Pro:
0
45
12
0
45
45
45
23
0
23
67
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
12
0
0
12
0
12
23
12
12
0
0
0
12
0
% S
% Thr:
0
12
0
12
0
0
0
0
0
23
0
0
0
0
0
% T
% Val:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _