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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
30.3
Human Site:
Y287
Identified Species:
55.56
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
Y287
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
Y287
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
Y287
G
D
Y
Q
G
D
Y
Y
A
P
G
S
N
Y
D
Dog
Lupus familis
XP_852897
464
51133
Y345
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
N271
L
S
E
L
G
H
T
N
R
I
Y
G
N
V
G
Rat
Rattus norvegicus
P63007
406
44762
Y287
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
E116
H
S
T
S
S
D
K
E
A
A
N
N
E
N
E
Chicken
Gallus gallus
P53411
406
44827
Y287
G
D
Y
Q
S
E
Y
Y
G
P
G
A
N
Y
E
Frog
Xenopus laevis
P29674
403
44916
Y286
G
D
Y
Q
S
E
Y
Y
G
P
G
S
N
Y
D
Zebra Danio
Brachydanio rerio
Q90476
405
45135
Y286
G
D
Y
Q
S
E
Y
Y
G
P
G
G
N
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
L160
T
T
F
T
E
E
Q
L
Q
V
L
Q
A
N
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
V284
E
T
G
L
N
M
R
V
I
Q
V
W
F
Q
N
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
H355
F
D
Y
F
H
P
G
H
P
N
G
P
P
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
73.3
100
N.A.
13.3
100
N.A.
6.6
86.6
93.3
100
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
80
100
N.A.
13.3
100
N.A.
20
93.3
93.3
100
N.A.
13.3
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
16
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
0
0
16
0
0
0
0
0
0
0
0
54
% D
% Glu:
8
0
8
0
8
62
0
8
0
0
0
0
8
0
16
% E
% Phe:
8
0
8
8
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
62
0
8
0
16
0
8
0
54
0
70
47
0
0
8
% G
% His:
8
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
16
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
8
8
8
70
16
8
% N
% Pro:
0
0
0
0
0
8
0
0
8
62
0
8
8
0
0
% P
% Gln:
0
0
0
62
0
0
8
0
8
8
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% R
% Ser:
0
16
0
8
62
0
0
0
0
0
0
16
0
8
8
% S
% Thr:
8
16
8
8
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
70
0
0
0
62
62
0
0
8
0
0
62
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _