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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHX1 All Species: 22.42
Human Site: S317 Identified Species: 41.11
UniProt: P48742 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P48742 NP_005559.2 406 44808 S317 D L P F V P S S G P S G T P L
Chimpanzee Pan troglodytes Q5IS44 406 44776 S317 D L P F V P S S G P S G T P L
Rhesus Macaque Macaca mulatta XP_001111705 402 44357 G317 S S F L A A S G P G S T P L G
Dog Lupus familis XP_852897 464 51133 S375 D L P F V P S S G P S G T P L
Cat Felis silvestris
Mouse Mus musculus P53776 390 43059 D301 G T G Q S Y Q D L R D G S P Y
Rat Rattus norvegicus P63007 406 44762 S317 D L P F V P S S G P S G T P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517055 231 26095 L146 K A K Q L E T L K A A F A A T
Chicken Gallus gallus P53411 406 44827 G317 E L P F G A A G G P P G T P L
Frog Xenopus laevis P29674 403 44916 S316 D L P F V P S S V P A G T P L
Zebra Danio Brachydanio rerio Q90476 405 45135 S316 D L P F V P S S G P T G T P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IRC7 275 31013 R190 S V T G L S K R V T Q V W F Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P20154 405 45759 R314 Y R Q S R R P R R D D I V D M
Sea Urchin Strong. purpuratus NP_999810 480 53702 N385 H P P V S Q G N H P M D H H I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 73.8 87.2 N.A. 36.2 99.5 N.A. 46.7 94.3 92.1 87.9 N.A. 31.7 N.A. 40.1 52.9
Protein Similarity: 100 99.7 84.4 87.2 N.A. 52.4 99.7 N.A. 52.4 96.8 96 94.3 N.A. 43.3 N.A. 54.9 62.7
P-Site Identity: 100 100 13.3 100 N.A. 13.3 100 N.A. 0 60 86.6 93.3 N.A. 0 N.A. 0 13.3
P-Site Similarity: 100 100 13.3 100 N.A. 20 100 N.A. 20 73.3 93.3 100 N.A. 13.3 N.A. 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 16 8 0 0 8 16 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 47 0 0 0 0 0 0 8 0 8 16 8 0 8 0 % D
% Glu: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 54 0 0 0 0 0 0 0 8 0 8 0 % F
% Gly: 8 0 8 8 8 0 8 16 47 8 0 62 0 0 8 % G
% His: 8 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % I
% Lys: 8 0 8 0 0 0 8 0 8 0 0 0 0 0 0 % K
% Leu: 0 54 0 8 16 0 0 8 8 0 0 0 0 8 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 62 0 0 47 8 0 8 62 8 0 8 62 0 % P
% Gln: 0 0 8 16 0 8 8 0 0 0 8 0 0 0 8 % Q
% Arg: 0 8 0 0 8 8 0 16 8 8 0 0 0 0 0 % R
% Ser: 16 8 0 8 16 8 54 47 0 0 39 0 8 0 0 % S
% Thr: 0 8 8 0 0 0 8 0 0 8 8 8 54 0 8 % T
% Val: 0 8 0 8 47 0 0 0 16 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _