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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
38.79
Human Site:
S242
Identified Species:
71.11
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Dog
Lupus familis
XP_852897
464
51133
S300
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
A219
E
K
R
L
K
K
D
A
G
R
H
R
W
G
Q
Rat
Rattus norvegicus
P63007
406
44762
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
G79
N
S
P
S
L
K
E
G
S
L
N
S
V
S
S
Chicken
Gallus gallus
P53411
406
44827
S242
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Frog
Xenopus laevis
P29674
403
44916
S241
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Zebra Danio
Brachydanio rerio
Q90476
405
45135
S241
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
Y123
R
V
L
C
K
A
H
Y
L
E
T
V
E
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
T246
A
K
R
R
G
P
R
T
T
I
K
A
K
Q
L
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
S294
E
R
R
M
K
Q
L
S
A
L
G
A
R
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
100
100
N.A.
20
100
N.A.
6.6
100
100
100
N.A.
6.6
N.A.
13.3
100
P-Site Similarity:
100
100
100
100
N.A.
46.6
100
N.A.
26.6
100
100
100
N.A.
6.6
N.A.
46.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
70
0
0
77
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
77
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
8
0
70
0
0
16
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
70
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
16
0
0
85
16
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
0
8
8
8
0
70
0
8
77
0
0
0
0
8
% L
% Met:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
70
0
0
0
0
0
0
0
8
8
% Q
% Arg:
8
70
85
8
0
0
8
0
0
8
0
8
70
70
0
% R
% Ser:
0
8
0
8
0
0
0
70
8
0
0
8
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _