KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX1
All Species:
18.18
Human Site:
S142
Identified Species:
33.33
UniProt:
P48742
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48742
NP_005559.2
406
44808
S142
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
S142
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
P143
C
T
D
R
S
L
S
P
D
L
Q
D
A
L
Q
Dog
Lupus familis
XP_852897
464
51133
S200
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
I119
L
H
C
F
A
C
I
I
C
N
R
Q
L
A
T
Rat
Rattus norvegicus
P63007
406
44762
S142
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
Chicken
Gallus gallus
P53411
406
44827
S142
T
G
S
D
P
S
L
S
P
D
S
Q
D
P
S
Frog
Xenopus laevis
P29674
403
44916
P142
G
S
D
P
S
L
S
P
E
S
Q
D
P
L
Q
Zebra Danio
Brachydanio rerio
Q90476
405
45135
P142
C
S
D
P
S
L
S
P
D
S
Q
D
Q
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IRC7
275
31013
C26
F
F
L
E
V
G
G
C
S
W
H
A
H
C
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
R122
C
K
T
D
F
S
R
R
Y
S
Q
R
C
A
G
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
C143
F
N
K
P
P
G
S
C
N
T
A
L
S
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
73.8
87.2
N.A.
36.2
99.5
N.A.
46.7
94.3
92.1
87.9
N.A.
31.7
N.A.
40.1
52.9
Protein Similarity:
100
99.7
84.4
87.2
N.A.
52.4
99.7
N.A.
52.4
96.8
96
94.3
N.A.
43.3
N.A.
54.9
62.7
P-Site Identity:
100
100
0
100
N.A.
6.6
100
N.A.
0
100
0
0
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
0
100
N.A.
26.6
100
N.A.
0
100
0
0
N.A.
6.6
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
8
8
8
16
0
% A
% Cys:
24
0
8
0
0
8
0
16
8
0
0
0
8
8
0
% C
% Asp:
0
0
24
47
0
0
0
0
16
39
0
24
39
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
16
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
39
0
0
0
16
8
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
24
39
0
0
8
0
8
8
24
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
24
47
0
0
24
39
0
0
0
8
39
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
31
47
8
0
24
% Q
% Arg:
0
0
0
8
0
0
8
8
0
0
8
8
0
0
0
% R
% Ser:
0
16
39
0
24
47
31
39
8
24
39
0
8
8
39
% S
% Thr:
39
8
8
0
0
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _