KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERPINB4
All Species:
8.48
Human Site:
T129
Identified Species:
26.67
UniProt:
P48594
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48594
NP_002965.1
390
44854
T129
A
I
K
K
F
Y
Q
T
S
V
E
S
T
D
F
Chimpanzee
Pan troglodytes
XP_001147882
390
44851
T129
A
I
K
K
F
Y
Q
T
S
V
E
S
V
D
F
Rhesus Macaque
Macaca mulatta
XP_001090785
390
44710
T129
A
I
K
K
F
Y
Q
T
S
V
E
S
V
D
F
Dog
Lupus familis
XP_541074
389
44529
A130
N
I
K
K
F
Y
L
A
S
V
E
S
V
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDC0
389
44313
A129
Y
V
E
K
Y
Y
H
A
S
L
E
P
V
D
F
Rat
Rattus norvegicus
Q4G075
379
42708
K130
H
A
S
E
D
A
R
K
E
I
N
Q
W
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P01014
388
43754
V130
R
K
F
Y
T
G
G
V
E
E
V
N
F
K
T
Frog
Xenopus laevis
Q52L45
377
42679
A129
F
I
S
A
L
E
D
A
R
K
E
I
N
K
W
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
90.2
67.6
N.A.
52
48.9
N.A.
N.A.
44
47.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
94.6
80.5
N.A.
74.6
63.8
N.A.
N.A.
62
65.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
40
0
N.A.
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
66.6
20
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
13
0
13
0
13
0
38
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
13
0
0
0
0
0
0
63
0
% D
% Glu:
0
0
13
13
0
13
0
0
25
13
75
0
0
0
0
% E
% Phe:
13
0
13
0
50
0
0
0
0
0
0
0
13
0
63
% F
% Gly:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% G
% His:
13
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% H
% Ile:
0
63
0
0
0
0
0
0
0
13
0
13
0
0
0
% I
% Lys:
0
13
50
63
0
0
0
13
0
13
0
0
0
25
13
% K
% Leu:
0
0
0
0
13
0
13
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
13
13
13
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
0
0
0
38
0
0
0
0
13
0
0
0
% Q
% Arg:
13
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% R
% Ser:
0
0
25
0
0
0
0
0
63
0
0
50
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
38
0
0
0
0
13
0
13
% T
% Val:
0
13
0
0
0
0
0
13
0
50
13
0
50
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% W
% Tyr:
13
0
0
13
13
63
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _