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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LSS
All Species:
19.39
Human Site:
S720
Identified Species:
35.56
UniProt:
P48449
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48449
NP_001001438.1
732
83309
S720
I
W
A
L
G
R
F
S
Q
L
Y
P
E
R
A
Chimpanzee
Pan troglodytes
XP_001159379
732
83231
S720
I
W
A
L
G
R
F
S
Q
L
Y
T
E
R
A
Rhesus Macaque
Macaca mulatta
XP_001098607
732
83143
S720
I
W
T
L
G
R
F
S
Q
L
Y
P
E
R
A
Dog
Lupus familis
XP_548733
654
72679
L644
T
L
G
R
F
S
R
L
Y
P
E
S
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLN5
733
83123
S721
I
W
A
L
G
R
F
S
N
L
Y
P
D
N
T
Rat
Rattus norvegicus
P48450
733
83282
S721
I
W
A
L
G
R
F
S
S
L
Y
P
D
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514164
568
63937
L558
G
L
G
R
L
V
V
L
R
P
E
G
G
T
P
Chicken
Gallus gallus
NP_001006514
676
76923
Q666
G
W
G
R
P
Q
R
Q
H
C
L
I
E
P
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001077036
735
83649
T721
V
W
T
L
G
R
F
T
R
L
Y
P
C
N
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193804
671
77348
D659
N
D
A
S
P
L
E
D
K
S
D
S
N
S
S
Poplar Tree
Populus trichocarpa
XP_002308131
761
86469
F743
Y
A
A
Y
R
D
I
F
P
I
W
A
L
G
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38605
759
86015
G747
I
F
P
I
W
A
L
G
E
Y
R
C
Q
V
L
Baker's Yeast
Sacchar. cerevisiae
P38604
731
83442
I705
V
F
N
H
S
C
A
I
E
Y
P
S
Y
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
47.8
N.A.
85.5
84.3
N.A.
57.3
69.8
N.A.
75.2
N.A.
N.A.
N.A.
N.A.
46.3
Protein Similarity:
100
99.4
99
59.9
N.A.
92.5
91.6
N.A.
64.6
78.4
N.A.
86.1
N.A.
N.A.
N.A.
N.A.
62.7
P-Site Identity:
100
93.3
93.3
6.6
N.A.
73.3
73.3
N.A.
0
13.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
6.6
N.A.
80
80
N.A.
6.6
20
N.A.
80
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
44.2
N.A.
N.A.
44.4
40.8
N.A.
Protein Similarity:
60.3
N.A.
N.A.
61.1
58
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
47
0
0
8
8
0
0
0
0
8
8
0
39
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
8
8
0
0
% C
% Asp:
0
8
0
0
0
8
0
8
0
0
8
0
16
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
16
0
16
0
31
0
8
% E
% Phe:
0
16
0
0
8
0
47
8
0
0
0
0
0
0
8
% F
% Gly:
16
0
24
0
47
0
0
8
0
0
0
8
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
47
0
0
8
0
0
8
8
0
8
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
16
0
47
8
8
8
16
0
47
8
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
0
0
0
0
0
8
0
0
0
8
24
0
% N
% Pro:
0
0
8
0
16
0
0
0
8
16
8
39
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
8
24
0
0
0
8
0
0
% Q
% Arg:
0
0
0
24
8
47
16
0
16
0
8
0
0
31
0
% R
% Ser:
0
0
0
8
8
8
0
39
8
8
0
24
0
8
8
% S
% Thr:
8
0
16
0
0
0
0
8
0
0
0
8
0
8
16
% T
% Val:
16
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
54
0
0
8
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
8
16
47
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _