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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RXRG
All Species:
38.48
Human Site:
Y398
Identified Species:
84.67
UniProt:
P48443
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48443
NP_008848.1
463
50871
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Chimpanzee
Pan troglodytes
XP_001174549
469
51415
Y404
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Rhesus Macaque
Macaca mulatta
XP_001085084
463
50825
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Dog
Lupus familis
XP_536146
463
50844
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
P28705
463
50875
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Rat
Rattus norvegicus
Q5BJR8
463
50875
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506054
433
47639
E372
E
K
V
Y
A
S
L
E
A
Y
C
K
H
K
Y
Chicken
Gallus gallus
P28701
467
51215
Y402
E
S
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Frog
Xenopus laevis
P51129
470
51907
Y405
E
A
L
R
E
K
V
Y
A
T
L
E
S
Y
T
Zebra Danio
Brachydanio rerio
Q90416
441
48702
Y376
E
A
L
R
E
K
V
Y
A
S
L
E
G
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20153
508
55226
Y437
E
M
C
R
E
K
V
Y
A
C
L
D
E
H
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.5
97.8
N.A.
98.2
97.6
N.A.
71.4
85.2
74.6
73
N.A.
40.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
100
98.9
N.A.
99.1
99.1
N.A.
80.1
91.2
84
81.4
N.A.
57.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
86.6
80
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
93.3
86.6
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
0
0
0
100
0
0
0
64
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
10
10
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
100
0
0
0
91
0
0
10
0
0
0
82
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
91
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
82
0
0
0
10
0
0
0
91
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
10
0
0
0
10
0
0
10
0
0
% S
% Thr:
0
55
0
0
0
0
0
0
0
73
0
0
0
0
82
% T
% Val:
0
0
10
0
0
0
91
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
91
0
10
0
0
0
82
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _