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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFX2
All Species:
4.55
Human Site:
S719
Identified Species:
10
UniProt:
P48378
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48378
NP_000626.2
723
79987
S719
E
R
S
D
P
N
H
S
L
Q
G
I
_
_
_
Chimpanzee
Pan troglodytes
XP_512310
715
78711
Rhesus Macaque
Macaca mulatta
XP_001086864
723
79802
S719
E
R
S
D
P
N
H
S
L
Q
G
I
_
_
_
Dog
Lupus familis
XP_533937
727
80183
Cat
Felis silvestris
Mouse
Mus musculus
P48379
717
79171
Rat
Rattus norvegicus
B2GV50
692
76518
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513118
644
72451
Chicken
Gallus gallus
XP_418212
701
78586
Frog
Xenopus laevis
Q32NR3
694
77765
Zebra Danio
Brachydanio rerio
Q5EAP5
734
81836
I727
V
K
R
E
R
I
E
I
P
H
S
L
Q
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09555
805
90889
A790
P
Q
E
Y
I
V
V
A
N
D
N
D
E
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
96.2
94.3
N.A.
87.8
86.1
N.A.
70.8
82.5
75.9
74.5
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
100
97.9
97
96.2
N.A.
91.9
89.9
N.A.
76.6
89.7
85.8
83.3
N.A.
N.A.
N.A.
47.5
N.A.
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
0
100
0
N.A.
0
0
N.A.
0
0
0
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
0
10
0
10
0
10
0
% D
% Glu:
19
0
10
10
0
0
10
0
0
0
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
10
0
10
0
0
0
19
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
19
0
0
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
0
10
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
19
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
19
0
0
10
0
0
% Q
% Arg:
0
19
10
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
0
0
0
0
19
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
19
19
19
% _