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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFPI2
All Species:
11.82
Human Site:
Y57
Identified Species:
28.89
UniProt:
P48307
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48307
NP_006519.1
235
26934
Y57
L
R
Y
Y
Y
D
R
Y
T
Q
S
C
R
Q
F
Chimpanzee
Pan troglodytes
XP_519205
235
26929
Y57
L
R
Y
Y
Y
D
R
Y
T
Q
S
C
R
Q
F
Rhesus Macaque
Macaca mulatta
Q28864
304
35067
F75
K
R
F
F
F
N
I
F
T
R
Q
C
E
E
F
Dog
Lupus familis
XP_532462
234
26129
Y57
P
S
Y
Y
Y
D
R
Y
T
Q
S
C
L
P
F
Cat
Felis silvestris
Mouse
Mus musculus
O35536
230
26119
D57
P
K
F
Y
Y
D
R
D
Q
Q
K
C
R
R
F
Rat
Rattus norvegicus
Q02445
302
34535
N74
R
S
Y
Y
F
N
M
N
S
H
Q
C
E
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516961
229
25362
Y60
P
S
Y
Y
Y
D
R
Y
T
Q
T
C
L
L
F
Chicken
Gallus gallus
XP_418662
238
26877
T55
R
W
Y
Y
D
R
Y
T
Q
S
C
Q
E
F
S
Frog
Xenopus laevis
NP_001079835
224
25520
C55
Y
D
R
Y
T
Q
T
C
Q
E
F
F
Y
G
G
Zebra Danio
Brachydanio rerio
NP_001035185
233
26599
E56
N
T
I
S
Q
Q
C
E
E
F
S
Y
S
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
30.2
70.2
N.A.
54
27.8
N.A.
51
46.6
48.5
39.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
46
78.7
N.A.
64.6
44
N.A.
64.6
62.1
64.2
58.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
73.3
N.A.
53.3
26.6
N.A.
66.6
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
73.3
N.A.
73.3
53.3
N.A.
73.3
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
10
70
0
0
10
% C
% Asp:
0
10
0
0
10
50
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
10
0
0
30
20
0
% E
% Phe:
0
0
20
10
20
0
0
10
0
10
10
10
0
10
70
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
20
0
0
0
0
0
0
0
0
0
0
0
20
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
20
0
10
0
0
0
0
0
0
0
% N
% Pro:
30
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
20
0
0
30
50
20
10
0
20
0
% Q
% Arg:
20
30
10
0
0
10
50
0
0
10
0
0
30
10
0
% R
% Ser:
0
30
0
10
0
0
0
0
10
10
40
0
10
0
10
% S
% Thr:
0
10
0
0
10
0
10
10
50
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
60
80
50
0
10
40
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _