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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJA8
All Species:
22.73
Human Site:
S258
Identified Species:
55.56
UniProt:
P48165
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48165
NP_005258.2
433
48229
S258
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Chimpanzee
Pan troglodytes
XP_524857
433
48312
S258
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Rhesus Macaque
Macaca mulatta
XP_001095298
435
48589
S264
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Dog
Lupus familis
XP_540274
439
48960
S265
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P28236
440
49579
S265
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Rat
Rattus norvegicus
Q8K4Q9
440
49383
S265
S
L
H
S
I
A
V
S
S
I
Q
K
A
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516993
294
32753
P140
Q
G
H
G
K
R
G
P
S
K
G
T
K
K
F
Chicken
Gallus gallus
P36381
400
45598
Q245
L
R
R
P
A
E
E
Q
M
G
E
V
P
E
K
Frog
Xenopus laevis
P51914
352
40615
F198
C
P
H
K
V
D
C
F
V
S
R
P
M
E
K
Zebra Danio
Brachydanio rerio
O57474
381
43436
E227
S
L
L
L
N
I
I
E
L
F
Y
V
L
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.9
87.9
N.A.
87.2
87.2
N.A.
51
72
38.5
41.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
96.3
92.2
N.A.
91.5
91.8
N.A.
57
79.4
54.2
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
60
0
0
0
0
0
0
60
0
0
% A
% Cys:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
10
0
0
10
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
10
% F
% Gly:
0
10
0
10
0
0
10
0
0
10
10
0
0
0
60
% G
% His:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
60
10
10
0
0
60
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
0
10
0
60
10
70
30
% K
% Leu:
10
70
10
10
0
0
0
0
10
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
10
0
0
0
10
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
60
0
0
0
0
% Q
% Arg:
0
10
10
0
0
10
0
0
0
0
10
0
0
0
0
% R
% Ser:
70
0
0
60
0
0
0
60
70
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
10
0
60
0
10
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _