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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREP
All Species:
31.82
Human Site:
Y90
Identified Species:
53.85
UniProt:
P48147
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48147
NP_002717.3
710
80700
Y90
G
K
R
Y
F
Y
F
Y
N
T
G
L
Q
N
Q
Chimpanzee
Pan troglodytes
XP_518657
710
80695
Y90
G
K
R
Y
F
Y
F
Y
N
T
G
L
Q
N
Q
Rhesus Macaque
Macaca mulatta
XP_001087580
710
80763
Y90
G
K
R
Y
F
Y
F
Y
N
T
G
L
Q
N
Q
Dog
Lupus familis
XP_854289
651
73567
M90
D
W
V
T
I
K
F
M
K
V
D
G
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR6
710
80733
Y90
G
K
R
Y
F
Y
F
Y
N
T
G
L
Q
N
Q
Rat
Rattus norvegicus
O70196
710
80723
Y90
G
K
R
Y
F
Y
F
Y
N
T
G
L
Q
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505853
734
82688
Y114
G
K
R
Y
F
Y
F
Y
N
S
G
L
Q
N
Q
Chicken
Gallus gallus
NP_001006410
710
80772
Y90
G
K
R
Y
F
H
F
Y
N
T
G
L
Q
N
Q
Frog
Xenopus laevis
NP_001084314
712
80625
Y93
G
K
R
Y
F
Y
F
Y
N
S
G
L
Q
N
Q
Zebra Danio
Brachydanio rerio
NP_001018589
709
80318
N95
F
Y
N
T
G
L
Q
N
Q
S
V
M
Y
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395364
765
87125
K150
G
N
K
Y
Y
F
Y
K
N
T
G
L
Q
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002306966
733
82736
H97
G
N
K
Y
F
Y
F
H
N
T
G
L
Q
A
Q
Maize
Zea mays
NP_001130392
731
81856
H98
G
N
K
Y
F
Y
F
H
N
S
G
L
Q
A
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177741
795
89386
H161
G
D
K
Y
F
Y
F
H
N
T
G
L
Q
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
87.6
N.A.
95.7
95.2
N.A.
86.2
90.2
81.5
76
N.A.
N.A.
55.2
N.A.
N.A.
Protein Similarity:
100
100
99.5
89.5
N.A.
98.5
98.3
N.A.
92.3
95.9
91
89.3
N.A.
N.A.
70.5
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
93.3
93.3
6.6
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
100
20
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
55.6
54.5
N.A.
52.4
N.A.
N.A.
Protein Similarity:
73.2
72.5
N.A.
68.1
N.A.
N.A.
P-Site Identity:
73.3
66.6
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
79
8
86
0
0
0
0
0
0
0
0
% F
% Gly:
86
0
0
0
8
0
0
0
0
0
86
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
22
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
58
29
0
0
8
0
8
8
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
0
86
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
22
8
0
0
0
0
8
86
0
0
0
0
65
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
86
0
93
% Q
% Arg:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
65
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
8
8
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
86
8
72
8
58
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _