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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREP
All Species:
42.42
Human Site:
Y76
Identified Species:
71.79
UniProt:
P48147
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48147
NP_002717.3
710
80700
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Chimpanzee
Pan troglodytes
XP_518657
710
80695
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Rhesus Macaque
Macaca mulatta
XP_001087580
710
80763
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Dog
Lupus familis
XP_854289
651
73567
G76
D
G
E
Y
F
A
Y
G
L
S
A
S
G
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR6
710
80733
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Rat
Rattus norvegicus
O70196
710
80723
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505853
734
82688
Y100
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Chicken
Gallus gallus
NP_001006410
710
80772
Y76
E
L
Y
D
Y
P
K
Y
S
C
H
F
K
K
G
Frog
Xenopus laevis
NP_001084314
712
80625
Y79
E
L
Y
D
Y
P
K
Y
S
C
N
F
K
K
G
Zebra Danio
Brachydanio rerio
NP_001018589
709
80318
R81
K
Y
S
C
P
F
K
R
G
D
R
Y
F
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395364
765
87125
Y136
Q
L
W
D
F
P
K
Y
S
C
P
A
R
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002306966
733
82736
Y83
K
L
F
D
H
P
R
Y
D
A
P
F
K
R
G
Maize
Zea mays
NP_001130392
731
81856
H84
R
L
F
D
H
P
R
H
A
A
P
F
R
R
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177741
795
89386
Y147
K
L
I
D
H
P
R
Y
D
S
P
F
R
Q
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
87.6
N.A.
95.7
95.2
N.A.
86.2
90.2
81.5
76
N.A.
N.A.
55.2
N.A.
N.A.
Protein Similarity:
100
100
99.5
89.5
N.A.
98.5
98.3
N.A.
92.3
95.9
91
89.3
N.A.
N.A.
70.5
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
100
100
93.3
6.6
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
100
100
100
20
N.A.
N.A.
80
N.A.
N.A.
Percent
Protein Identity:
55.6
54.5
N.A.
52.4
N.A.
N.A.
Protein Similarity:
73.2
72.5
N.A.
68.1
N.A.
N.A.
P-Site Identity:
46.6
33.3
N.A.
40
N.A.
N.A.
P-Site Similarity:
80
80
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
15
8
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
65
0
0
0
0
0
% C
% Asp:
8
0
0
86
0
0
0
0
15
8
0
0
0
0
8
% D
% Glu:
58
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
15
8
0
0
0
0
0
79
8
0
8
% F
% Gly:
0
8
0
0
0
0
0
8
8
0
0
0
8
0
86
% G
% His:
0
0
0
0
22
0
0
8
0
0
50
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
22
0
0
0
0
0
72
0
0
0
0
0
65
58
0
% K
% Leu:
0
86
0
0
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
8
86
0
0
0
0
29
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
0
0
22
8
0
0
8
0
22
15
0
% R
% Ser:
0
0
8
0
0
0
0
0
65
15
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
58
8
58
0
8
79
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _