Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XDH All Species: 33.33
Human Site: Y1228 Identified Species: 73.33
UniProt: P47989 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P47989 NP_000370.2 1333 146424 Y1228 H T R G P S T Y K I P A F G S
Chimpanzee Pan troglodytes XP_525729 1333 146376 Y1228 H T R G P S T Y K I P A F G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540143 1333 147201 Y1229 Q T R G P S T Y K I P A F G N
Cat Felis silvestris
Mouse Mus musculus Q00519 1335 146500 Y1230 H T R G P S T Y K I P A F G S
Rat Rattus norvegicus P22985 1331 146224 Y1227 H T R G P S T Y K I P A F G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509432 1297 142673 Y1192 L T R G L D S Y K I P A C G D
Chicken Gallus gallus P47990 1358 149595 Y1256 Y T R G P G M Y K I P A F G D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688983 1351 148155 Y1249 Y T R G P G M Y K I P A F G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10351 1335 146909 Y1233 Y S R G P G M Y K L P G F A D
Honey Bee Apis mellifera XP_001119950 1356 152206 A1249 Y L R N G A I A T R G P G A Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7G192 1321 144562 Y1215 L T D S T W T Y K I P T V D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 90.4 N.A. 89.1 90.3 N.A. 70.4 72.3 N.A. 67.8 N.A. 52.6 52.4 N.A. N.A.
Protein Similarity: 100 99.6 N.A. 95.4 N.A. 95.1 95.8 N.A. 82.3 84 N.A. 81.4 N.A. 69.5 70.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 100 100 N.A. 60 73.3 N.A. 73.3 N.A. 46.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 66.6 80 N.A. 80 N.A. 66.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 10 0 0 0 73 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 10 0 0 10 0 0 0 0 0 0 0 10 37 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 % F
% Gly: 0 0 0 82 10 28 0 0 0 0 10 10 10 73 0 % G
% His: 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 82 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 % K
% Leu: 19 10 0 0 10 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 73 0 0 0 0 0 91 10 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 91 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 10 0 10 0 46 10 0 0 0 0 0 0 0 37 % S
% Thr: 0 82 0 0 10 0 55 0 10 0 0 10 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 37 0 0 0 0 0 0 91 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _