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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP1B All Species: 10.91
Human Site: Y1227 Identified Species: 30
UniProt: P46821 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46821 NP_005900.2 2468 270620 Y1227 R S A L R D A Y C S E V K A S
Chimpanzee Pan troglodytes XP_517716 2485 272422 Y1244 R S A L R D A Y C S E V K A S
Rhesus Macaque Macaca mulatta XP_001097124 2246 245764 I1021 T L D I K D T I S A V S G G K
Dog Lupus familis XP_862172 2248 245736 T1023 A T L A I R D T I S A V S E E
Cat Felis silvestris
Mouse Mus musculus P14873 2464 270392 Y1223 K S A L R D A Y C S E E K E L
Rat Rattus norvegicus P15205 2459 269481 A1218 S K S A L R D A Y R P E E T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512735 1203 127708
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121673 2033 222081 M808 E A L K A E E M A E D D E V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W596 5495 592060 S3616 R E S V A E K S P L A S K E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 89.3 82.9 N.A. 90.4 89.7 N.A. 27.4 N.A. N.A. 50.6 N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 99.1 89.8 85.6 N.A. 93.5 92.9 N.A. 36.9 N.A. N.A. 63.7 N.A. 31.3 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 73.3 0 N.A. 0 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 80 13.3 N.A. 0 N.A. N.A. 26.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 34 23 23 0 34 12 12 12 23 0 0 23 12 % A
% Cys: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 45 23 0 0 0 12 12 0 0 12 % D
% Glu: 12 12 0 0 0 23 12 0 0 12 34 23 23 34 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 12 0 0 12 12 0 0 0 0 0 0 % I
% Lys: 12 12 0 12 12 0 12 0 0 0 0 0 45 0 12 % K
% Leu: 0 12 23 34 12 0 0 0 0 12 0 0 0 0 23 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 0 12 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 34 0 0 0 34 23 0 0 0 12 0 0 0 0 0 % R
% Ser: 12 34 23 0 0 0 0 12 12 45 0 23 12 0 23 % S
% Thr: 12 12 0 0 0 0 12 12 0 0 0 0 0 12 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 12 34 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 34 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _