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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHKA1
All Species:
26.97
Human Site:
S605
Identified Species:
53.94
UniProt:
P46020
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46020
NP_001116142.1
1223
137312
S605
R
V
Q
T
G
K
L
S
E
F
L
T
T
S
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094193
1223
137165
S605
R
V
Q
T
G
K
L
S
E
F
L
T
T
S
C
Dog
Lupus familis
XP_859262
1222
136896
S605
R
I
Q
T
G
K
L
S
E
F
L
T
T
S
C
Cat
Felis silvestris
Mouse
Mus musculus
P18826
1241
138774
E606
I
Q
T
G
K
L
S
E
F
L
T
T
S
C
C
Rat
Rattus norvegicus
Q64649
1242
139137
E607
I
Q
T
G
K
L
S
E
F
L
T
T
S
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514153
1339
149225
S708
R
V
K
L
G
K
L
S
E
F
L
T
T
S
F
Chicken
Gallus gallus
XP_416811
1230
138135
S605
R
V
K
I
G
K
L
S
E
F
L
T
T
S
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923412
1219
136932
S605
R
V
Q
T
G
K
L
S
E
F
L
T
T
C
C
Tiger Blowfish
Takifugu rubipres
Q9W6R1
1229
137905
S605
R
V
Q
M
S
D
L
S
T
F
Q
T
T
S
F
Fruit Fly
Dros. melanogaster
Q9W391
1247
140494
F605
M
L
G
S
L
K
D
F
L
N
T
S
A
I
T
Honey Bee
Apis mellifera
XP_623102
1197
134419
S599
Y
I
N
G
T
R
V
S
L
G
N
L
N
D
F
Nematode Worm
Caenorhab. elegans
P34335
1226
139432
S612
K
I
N
T
G
Y
L
S
G
A
R
V
V
M
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
95.6
N.A.
93.3
92.5
N.A.
63.4
67.9
N.A.
70
67.2
50.3
50
40.5
N.A.
Protein Similarity:
100
N.A.
99
98
N.A.
96.1
95.9
N.A.
74.8
81
N.A.
83.3
79.5
67.2
67.6
59.3
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
13.3
13.3
N.A.
80
80
N.A.
93.3
60
6.6
6.6
26.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
20
20
N.A.
86.6
86.6
N.A.
93.3
60
26.6
26.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
50
% C
% Asp:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
17
50
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
17
59
0
0
0
0
34
% F
% Gly:
0
0
9
25
59
0
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
25
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
9
0
17
0
17
59
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
9
0
9
9
17
67
0
17
17
50
9
0
0
0
% L
% Met:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
9
9
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
42
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
59
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
9
9
0
17
75
0
0
0
9
17
50
0
% S
% Thr:
0
0
17
42
9
0
0
0
9
0
25
75
59
0
9
% T
% Val:
0
50
0
0
0
0
9
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _