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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHKA1 All Species: 9.09
Human Site: S581 Identified Species: 18.18
UniProt: P46020 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46020 NP_001116142.1 1223 137312 S581 D G T S L N S S I L A A L R K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094193 1223 137165 S581 D G T S L N S S I L A A L R K
Dog Lupus familis XP_859262 1222 136896 S581 D G T S L N S S I L A A L R K
Cat Felis silvestris
Mouse Mus musculus P18826 1241 138774 I582 G T S L N S S I L A A L R K M
Rat Rattus norvegicus Q64649 1242 139137 I583 G A S L N S S I L A A L R K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514153 1339 149225 A684 D G S D I D S A V L A T V R K
Chicken Gallus gallus XP_416811 1230 138135 A581 D G T D I H P A V L A T I R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001923412 1219 136932 A581 D H T D L D P A V L A T L K K
Tiger Blowfish Takifugu rubipres Q9W6R1 1229 137905 C581 D G D A V D P C I L S T L R K
Fruit Fly Dros. melanogaster Q9W391 1247 140494 I581 D K I P L A M I Q T M R K L K
Honey Bee Apis mellifera XP_623102 1197 134419 G575 T H N H L D Q G K I P L A M I
Nematode Worm Caenorhab. elegans P34335 1226 139432 N588 E G L S H F S N I H L N R H M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 95.6 N.A. 93.3 92.5 N.A. 63.4 67.9 N.A. 70 67.2 50.3 50 40.5 N.A.
Protein Similarity: 100 N.A. 99 98 N.A. 96.1 95.9 N.A. 74.8 81 N.A. 83.3 79.5 67.2 67.6 59.3 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 13.3 13.3 N.A. 46.6 46.6 N.A. 46.6 46.6 20 6.6 26.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 40 40 N.A. 86.6 80 N.A. 73.3 73.3 20 20 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 0 25 0 17 67 25 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 67 0 9 25 0 34 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 59 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 17 0 9 9 9 0 0 0 9 0 0 0 9 0 % H
% Ile: 0 0 9 0 17 0 0 25 42 9 0 0 9 0 9 % I
% Lys: 0 9 0 0 0 0 0 0 9 0 0 0 9 25 67 % K
% Leu: 0 0 9 17 50 0 0 0 17 59 9 25 42 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 9 0 0 9 25 % M
% Asn: 0 0 9 0 17 25 0 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 9 0 0 25 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 25 50 0 % R
% Ser: 0 0 25 34 0 17 59 25 0 0 9 0 0 0 0 % S
% Thr: 9 9 42 0 0 0 0 0 0 9 0 34 0 0 0 % T
% Val: 0 0 0 0 9 0 0 0 25 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _