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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K4
All Species:
8.48
Human Site:
T20
Identified Species:
13.33
UniProt:
P45985
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45985
NP_003001.1
399
44288
T20
G
G
G
S
G
S
G
T
P
G
P
V
G
S
P
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
E27
V
N
G
T
S
S
A
E
T
N
L
E
A
L
Q
Rhesus Macaque
Macaca mulatta
XP_001114292
410
45566
T20
G
G
G
S
G
S
G
T
P
G
P
V
G
S
P
Dog
Lupus familis
XP_546627
413
46697
S22
V
S
G
L
L
G
N
S
H
Y
P
V
D
R
P
Cat
Felis silvestris
Mouse
Mus musculus
P47809
397
44095
G20
G
G
G
G
G
T
P
G
P
I
G
P
P
A
S
Rat
Rattus norvegicus
Q4KSH7
419
47517
E20
L
E
A
K
L
K
Q
E
N
R
E
A
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90891
398
44059
G21
I
T
P
S
P
A
E
G
P
G
P
G
G
S
A
Frog
Xenopus laevis
Q07192
446
50082
A32
S
G
S
S
G
S
S
A
G
L
G
F
Q
G
Q
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477353
424
47515
S44
T
S
S
T
S
S
G
S
T
S
S
G
S
S
S
Honey Bee
Apis mellifera
XP_394054
436
49631
F20
T
Q
S
S
S
R
Q
F
N
F
Q
H
L
D
F
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
Sea Urchin
Strong. purpuratus
XP_794490
382
43817
K20
G
R
G
R
L
S
L
K
L
K
I
H
T
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
S40
V
K
R
T
S
S
T
S
S
H
Y
N
N
I
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.3
97.3
89.3
N.A.
97.9
41.7
N.A.
N.A.
36.5
77.3
48.3
N.A.
54
55.9
44.6
55.8
Protein Similarity:
100
53.6
97.3
90.5
N.A.
98.2
57.2
N.A.
N.A.
53.8
80.9
64.4
N.A.
65.8
68.8
61.6
71.1
P-Site Identity:
100
13.3
100
26.6
N.A.
33.3
0
N.A.
N.A.
40
26.6
0
N.A.
20
6.6
0
26.6
P-Site Similarity:
100
20
100
33.3
N.A.
46.6
0
N.A.
N.A.
46.6
26.6
0
N.A.
33.3
6.6
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.3
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
7
7
0
0
0
7
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% D
% Glu:
0
7
0
0
0
0
7
14
0
0
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
7
0
7
0
0
7
% F
% Gly:
27
27
40
7
27
7
20
14
7
20
14
14
20
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
14
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% I
% Lys:
0
7
0
7
0
7
0
7
0
7
0
0
0
0
0
% K
% Leu:
7
0
0
7
20
0
7
0
7
7
7
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
14
7
0
7
7
0
7
% N
% Pro:
0
0
7
0
7
0
7
0
27
0
27
7
7
0
20
% P
% Gln:
0
7
0
0
0
0
14
0
0
0
7
0
7
0
14
% Q
% Arg:
0
7
7
7
0
7
0
0
0
7
0
0
7
14
7
% R
% Ser:
7
14
20
34
27
47
7
20
7
7
7
0
7
34
14
% S
% Thr:
14
7
0
20
0
7
7
14
14
0
0
0
7
0
7
% T
% Val:
20
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _