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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K4
All Species:
13.33
Human Site:
S5
Identified Species:
20.95
UniProt:
P45985
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45985
NP_003001.1
399
44288
S5
_
_
_
M
A
A
P
S
P
S
G
G
G
G
S
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
N12
K
P
T
P
I
Q
L
N
P
A
P
D
G
S
A
Rhesus Macaque
Macaca mulatta
XP_001114292
410
45566
S5
_
_
_
M
A
A
P
S
P
S
G
G
G
G
S
Dog
Lupus familis
XP_546627
413
46697
N7
_
M
E
N
S
C
C
N
I
L
T
S
E
N
D
Cat
Felis silvestris
Mouse
Mus musculus
P47809
397
44095
S5
_
_
_
M
A
A
P
S
P
S
G
G
G
G
S
Rat
Rattus norvegicus
Q4KSH7
419
47517
S5
_
_
_
M
A
A
S
S
L
E
Q
K
L
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90891
398
44059
K6
_
_
M
P
A
K
R
K
P
V
L
P
A
L
T
Frog
Xenopus laevis
Q07192
446
50082
L17
L
H
L
V
A
N
I
L
T
M
A
T
S
N
P
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477353
424
47515
S29
Q
L
S
L
N
N
L
S
I
R
H
P
P
S
S
Honey Bee
Apis mellifera
XP_394054
436
49631
R5
_
_
_
M
T
E
N
R
G
N
F
S
T
P
T
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
Sea Urchin
Strong. purpuratus
XP_794490
382
43817
N5
_
_
_
M
A
L
A
N
R
D
R
D
A
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
T25
S
I
Q
L
N
E
Q
T
G
S
D
N
G
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.3
97.3
89.3
N.A.
97.9
41.7
N.A.
N.A.
36.5
77.3
48.3
N.A.
54
55.9
44.6
55.8
Protein Similarity:
100
53.6
97.3
90.5
N.A.
98.2
57.2
N.A.
N.A.
53.8
80.9
64.4
N.A.
65.8
68.8
61.6
71.1
P-Site Identity:
100
13.3
100
0
N.A.
100
33.3
N.A.
N.A.
15.3
6.6
0
N.A.
13.3
8.3
0
16.6
P-Site Similarity:
100
33.3
100
14.2
N.A.
100
33.3
N.A.
N.A.
23
13.3
0
N.A.
20
25
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.3
38.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
47
27
7
0
0
7
7
0
14
0
20
% A
% Cys:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
7
14
0
0
7
% D
% Glu:
0
0
7
0
0
14
0
0
0
7
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
20
20
34
20
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
7
0
14
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
7
0
7
0
0
0
7
0
0
0
% K
% Leu:
7
7
7
14
0
7
14
7
7
7
7
0
7
7
0
% L
% Met:
0
7
7
40
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
14
14
7
20
0
7
0
7
0
14
0
% N
% Pro:
0
7
0
14
0
0
20
0
34
0
7
14
7
7
7
% P
% Gln:
7
0
7
0
0
7
7
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
7
7
7
0
0
0
7
% R
% Ser:
7
0
7
0
7
0
7
34
0
27
0
14
7
27
27
% S
% Thr:
0
0
7
0
7
0
0
7
7
0
7
7
7
0
14
% T
% Val:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
54
47
40
0
0
0
0
0
0
0
0
0
0
0
0
% _