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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBX5
All Species:
19.09
Human Site:
Y70
Identified Species:
52.5
UniProt:
P45973
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45973
NP_001120793.1
191
22225
Y70
I
S
E
F
M
K
K
Y
K
K
M
K
E
G
E
Chimpanzee
Pan troglodytes
XP_001161192
173
19690
F66
C
P
E
L
I
E
A
F
L
N
S
Q
K
A
G
Rhesus Macaque
Macaca mulatta
XP_001091785
283
31521
Y163
I
S
E
F
M
K
K
Y
K
K
M
K
E
G
E
Dog
Lupus familis
XP_534787
190
22105
Y70
I
S
E
F
M
K
K
Y
K
K
M
K
E
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61686
191
22167
Y70
I
S
E
F
M
K
K
Y
K
K
M
K
E
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508853
184
20945
P70
P
E
E
N
L
D
C
P
E
L
I
E
A
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080863
199
22766
Y86
I
S
E
F
M
K
K
Y
K
K
A
K
E
A
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P05205
206
23167
R74
I
Q
Q
Y
E
A
S
R
K
D
E
E
K
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q946J8
445
48626
S158
V
I
D
A
F
E
G
S
L
K
P
G
K
P
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
67.1
98.9
N.A.
97.9
N.A.
N.A.
64.4
N.A.
77.8
N.A.
N.A.
46.1
N.A.
N.A.
N.A.
Protein Similarity:
100
73.3
67.1
99.4
N.A.
99.4
N.A.
N.A.
75.9
N.A.
86.9
N.A.
N.A.
62.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
86.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
33.3
N.A.
86.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
28.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
12
0
0
0
12
0
12
23
12
% A
% Cys:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
12
78
0
12
23
0
0
12
0
12
23
56
0
56
% E
% Phe:
0
0
0
56
12
0
0
12
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
12
0
45
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
67
12
0
0
12
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
56
56
0
67
67
0
56
34
0
0
% K
% Leu:
0
0
0
12
12
0
0
0
23
12
0
0
0
0
12
% L
% Met:
0
0
0
0
56
0
0
0
0
0
45
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
12
12
0
0
0
0
0
12
0
0
12
0
0
12
0
% P
% Gln:
0
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
56
0
0
0
0
12
12
0
0
12
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _