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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG1
All Species:
39.7
Human Site:
Y598
Identified Species:
72.78
UniProt:
P45844
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45844
NP_004906.3
678
75592
Y598
T
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Chimpanzee
Pan troglodytes
XP_514918
823
91569
Y743
T
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
Y569
S
W
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
Dog
Lupus familis
XP_544902
661
73719
Y581
T
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64343
666
74015
Y586
A
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Rat
Rattus norvegicus
Q80W57
657
72942
Y570
P
W
L
S
W
L
Q
Y
F
S
I
P
R
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510754
656
73357
Y576
A
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Chicken
Gallus gallus
XP_416742
666
74499
Y586
T
Y
L
Q
W
M
S
Y
I
S
Y
V
R
Y
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103924
673
75388
Y593
K
Y
L
Q
W
I
S
Y
I
S
Y
V
R
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
Y606
V
Y
L
K
W
L
S
Y
L
S
W
F
R
Y
A
Honey Bee
Apis mellifera
XP_623409
623
69754
Y544
K
Y
L
K
F
L
S
Y
V
S
Y
V
R
Y
S
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
G519
S
L
S
Y
F
K
Y
G
Y
E
A
L
A
I
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6W5
648
72600
F568
Y
V
Q
Q
I
P
P
F
I
V
W
L
K
Y
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
28
94.6
N.A.
95.1
28.3
N.A.
92.6
91
N.A.
84.6
N.A.
30.2
51.9
25.5
N.A.
Protein Similarity:
100
80.9
52.6
95.7
N.A.
96.7
51.1
N.A.
94.4
94.5
N.A.
92.1
N.A.
53.2
70.5
47
N.A.
P-Site Identity:
100
100
46.6
100
N.A.
93.3
46.6
N.A.
93.3
100
N.A.
86.6
N.A.
53.3
60
0
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
93.3
60
N.A.
93.3
100
N.A.
93.3
N.A.
80
86.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
16
0
0
8
16
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
62
0
16
0
0
8
0
% I
% Lys:
16
0
0
16
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
8
85
0
0
31
0
0
8
0
0
16
0
0
8
% L
% Met:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
8
8
0
0
0
0
16
0
0
0
% P
% Gln:
0
0
8
62
0
0
16
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% R
% Ser:
16
0
8
16
0
0
70
0
0
85
0
0
0
0
8
% S
% Thr:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
8
8
0
62
0
0
0
% V
% Trp:
0
16
0
0
77
0
0
0
0
0
16
0
0
0
0
% W
% Tyr:
8
70
0
8
0
0
8
85
8
0
62
0
0
93
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _