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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG1
All Species:
31.21
Human Site:
Y498
Identified Species:
57.22
UniProt:
P45844
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45844
NP_004906.3
678
75592
Y498
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Chimpanzee
Pan troglodytes
XP_514918
823
91569
Y643
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
F469
Y
Y
R
V
S
S
Y
F
F
G
K
L
L
S
D
Dog
Lupus familis
XP_544902
661
73719
Y481
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64343
666
74015
Y486
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Rat
Rattus norvegicus
Q80W57
657
72942
F470
Y
Y
R
V
S
S
Y
F
F
G
K
L
V
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510754
656
73357
Y476
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Chicken
Gallus gallus
XP_416742
666
74499
Y486
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103924
673
75388
Y493
Y
W
Y
S
L
K
A
Y
Y
L
A
K
T
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
Y506
R
L
Y
R
C
D
T
Y
F
L
G
K
T
I
A
Honey Bee
Apis mellifera
XP_623409
623
69754
A444
N
Y
W
Y
S
V
K
A
Y
Y
L
A
R
T
L
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
A419
Y
F
L
A
K
N
I
A
E
L
P
Q
Y
I
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6W5
648
72600
S468
M
L
I
K
E
R
S
S
G
M
Y
R
L
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
28
94.6
N.A.
95.1
28.3
N.A.
92.6
91
N.A.
84.6
N.A.
30.2
51.9
25.5
N.A.
Protein Similarity:
100
80.9
52.6
95.7
N.A.
96.7
51.1
N.A.
94.4
94.5
N.A.
92.1
N.A.
53.2
70.5
47
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
100
100
N.A.
100
N.A.
40
6.6
13.3
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
26.6
N.A.
100
100
N.A.
100
N.A.
53.3
20
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
54
16
0
0
54
8
0
0
62
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% D
% Glu:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
16
24
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
16
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
0
0
0
16
8
% I
% Lys:
0
0
0
8
8
54
8
0
0
0
16
62
0
0
0
% K
% Leu:
0
16
8
0
54
0
0
0
0
70
8
16
16
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
16
8
0
8
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
54
24
16
8
8
0
0
0
0
0
24
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
62
8
0
% T
% Val:
0
0
0
16
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
54
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
24
62
8
0
0
16
62
62
8
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _