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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG1
All Species:
13.03
Human Site:
T46
Identified Species:
23.89
UniProt:
P45844
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45844
NP_004906.3
678
75592
T46
S
N
M
E
A
T
E
T
D
L
L
N
G
H
L
Chimpanzee
Pan troglodytes
XP_514918
823
91569
T203
S
N
M
E
A
T
E
T
D
L
L
N
G
H
L
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
R45
S
F
H
N
I
C
Y
R
V
K
V
K
S
G
F
Dog
Lupus familis
XP_544902
661
73719
G46
T
E
T
D
L
L
N
G
H
L
K
K
V
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64343
666
74015
T46
S
N
V
D
E
V
E
T
D
L
L
N
G
H
L
Rat
Rattus norvegicus
Q80W57
657
72942
V46
F
H
H
I
T
Y
R
V
K
V
K
S
G
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510754
656
73357
S46
T
E
A
Q
R
F
S
S
L
P
R
R
A
A
V
Chicken
Gallus gallus
XP_416742
666
74499
I46
N
G
T
D
N
Q
D
I
R
L
I
N
G
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103924
673
75388
T53
N
H
V
S
S
Q
Q
T
P
L
L
H
A
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
G58
P
S
P
P
E
D
S
G
S
G
S
G
Q
L
A
Honey Bee
Apis mellifera
XP_623409
623
69754
L22
G
K
R
P
A
V
T
L
T
H
L
P
K
R
P
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6W5
648
72600
Q45
I
T
S
Q
P
G
L
Q
M
S
M
Y
P
I
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
28
94.6
N.A.
95.1
28.3
N.A.
92.6
91
N.A.
84.6
N.A.
30.2
51.9
25.5
N.A.
Protein Similarity:
100
80.9
52.6
95.7
N.A.
96.7
51.1
N.A.
94.4
94.5
N.A.
92.1
N.A.
53.2
70.5
47
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
73.3
13.3
N.A.
0
33.3
N.A.
33.3
N.A.
0
13.3
0
N.A.
P-Site Similarity:
100
100
13.3
20
N.A.
86.6
33.3
N.A.
26.6
60
N.A.
73.3
N.A.
6.6
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
24
0
0
0
0
0
0
0
16
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
8
8
0
24
0
0
0
0
8
0
% D
% Glu:
0
16
0
16
16
0
24
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
8
0
0
0
8
0
16
0
8
0
8
39
8
0
% G
% His:
0
16
16
0
0
0
0
0
8
8
0
8
0
39
0
% H
% Ile:
8
0
0
8
8
0
0
8
0
0
8
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
0
0
8
8
16
16
8
0
0
% K
% Leu:
0
0
0
0
8
8
8
8
8
47
39
0
0
8
47
% L
% Met:
0
0
16
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
16
24
0
8
8
0
8
0
0
0
0
31
0
0
8
% N
% Pro:
8
0
8
16
8
0
0
0
8
8
0
8
8
0
8
% P
% Gln:
0
0
0
16
0
16
8
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
0
8
0
8
8
8
0
8
8
0
8
0
% R
% Ser:
31
8
8
8
8
0
16
8
8
8
8
8
8
0
0
% S
% Thr:
16
8
16
0
8
16
8
31
8
0
0
0
0
0
8
% T
% Val:
0
0
16
0
0
16
0
8
8
8
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _