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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG1 All Species: 2.12
Human Site: T378 Identified Species: 3.89
UniProt: P45844 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45844 NP_004906.3 678 75592 T378 P S E E V K Q T K R L K G L R
Chimpanzee Pan troglodytes XP_514918 823 91569 F523 G D A E V N P F L W H R P S E
Rhesus Macaque Macaca mulatta Q5MB13 654 72441 L349 Y K E T K A E L H Q L S G G E
Dog Lupus familis XP_544902 661 73719 F361 G D A E V N P F L W H R P S E
Cat Felis silvestris
Mouse Mus musculus Q64343 666 74015 F366 G D T D V N P F L W H R P A E
Rat Rattus norvegicus Q80W57 657 72942 D350 G E T K A E L D Q L P V A Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510754 656 73357 A356 P S E E V K Q A K R I K G L R
Chicken Gallus gallus XP_416742 666 74499 F366 G E N E L N P F L W H R P S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103924 673 75388 F373 G N G V H N P F L W H R P S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10090 687 75654 L386 V A R D M E Q L L A T K N L E
Honey Bee Apis mellifera XP_623409 623 69754 P324 S G T V I N I P I S C T T S L
Nematode Worm Caenorhab. elegans Q11180 598 66888 T299 S F V T G S D T S E K T K T F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6W5 648 72600 S348 S A Y E K N I S T K L K A E L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.9 28 94.6 N.A. 95.1 28.3 N.A. 92.6 91 N.A. 84.6 N.A. 30.2 51.9 25.5 N.A.
Protein Similarity: 100 80.9 52.6 95.7 N.A. 96.7 51.1 N.A. 94.4 94.5 N.A. 92.1 N.A. 53.2 70.5 47 N.A.
P-Site Identity: 100 13.3 20 13.3 N.A. 6.6 0 N.A. 86.6 6.6 N.A. 0 N.A. 20 0 6.6 N.A.
P-Site Similarity: 100 20 33.3 20 N.A. 20 26.6 N.A. 93.3 20 N.A. 13.3 N.A. 46.6 6.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 0 8 8 0 8 0 8 0 0 16 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 24 0 16 0 0 8 8 0 0 0 0 0 0 8 % D
% Glu: 0 16 24 47 0 16 8 0 0 8 0 0 0 8 47 % E
% Phe: 0 8 0 0 0 0 0 39 0 0 0 0 0 0 8 % F
% Gly: 47 8 8 0 8 0 0 0 0 0 0 0 24 8 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 39 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 16 0 8 0 8 0 0 0 0 % I
% Lys: 0 8 0 8 16 16 0 0 16 8 8 31 8 0 8 % K
% Leu: 0 0 0 0 8 0 8 16 47 8 24 0 0 24 16 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 54 0 0 0 0 0 0 8 0 0 % N
% Pro: 16 0 0 0 0 0 39 8 0 0 8 0 39 0 0 % P
% Gln: 0 0 0 0 0 0 24 0 8 8 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 16 0 39 0 0 16 % R
% Ser: 24 16 0 0 0 8 0 8 8 8 0 8 0 39 0 % S
% Thr: 0 0 24 16 0 0 0 16 8 0 8 16 8 8 0 % T
% Val: 8 0 8 16 39 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _