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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG1 All Species: 19.09
Human Site: S68 Identified Species: 35
UniProt: P45844 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45844 NP_004906.3 678 75592 S68 T E A Q R F S S L P R R A A V
Chimpanzee Pan troglodytes XP_514918 823 91569 S225 T E A Q R F S S L P R R A A V
Rhesus Macaque Macaca mulatta Q5MB13 654 72441 I67 E K E I L S N I N G I M K P G
Dog Lupus familis XP_544902 661 73719 A68 F S S L P R R A A V N I E F K
Cat Felis silvestris
Mouse Mus musculus Q64343 666 74015 S68 T E A Q R F S S L P R R A A V
Rat Rattus norvegicus Q80W57 657 72942 G68 E I L S D I N G I M K P G L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510754 656 73357 P68 S Y S V P E G P W W R K K G Y
Chicken Gallus gallus XP_416742 666 74499 Y68 T E A H R F S Y L P R R P A V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103924 673 75388 Y75 T E A Q R F S Y L P R R P A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10090 687 75654 A80 H N M D I F G A V N Q P G S G
Honey Bee Apis mellifera XP_623409 623 69754 E44 N L A Y S V S E G R K R G Y K
Nematode Worm Caenorhab. elegans Q11180 598 66888 S19 N V S G M A E S G K L L A I L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6W5 648 72600 T67 Y K V K I E Q T S Q C M G S W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.9 28 94.6 N.A. 95.1 28.3 N.A. 92.6 91 N.A. 84.6 N.A. 30.2 51.9 25.5 N.A.
Protein Similarity: 100 80.9 52.6 95.7 N.A. 96.7 51.1 N.A. 94.4 94.5 N.A. 92.1 N.A. 53.2 70.5 47 N.A.
P-Site Identity: 100 100 0 0 N.A. 100 0 N.A. 6.6 80 N.A. 86.6 N.A. 6.6 20 13.3 N.A.
P-Site Similarity: 100 100 13.3 13.3 N.A. 100 20 N.A. 26.6 80 N.A. 86.6 N.A. 33.3 26.6 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 47 0 0 8 0 16 8 0 0 0 31 39 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 16 39 8 0 0 16 8 8 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 47 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 8 0 0 16 8 16 8 0 0 31 8 16 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 16 8 0 8 8 0 8 8 0 8 0 % I
% Lys: 0 16 0 8 0 0 0 0 0 8 16 8 16 0 16 % K
% Leu: 0 8 8 8 8 0 0 0 39 0 8 8 0 8 8 % L
% Met: 0 0 8 0 8 0 0 0 0 8 0 16 0 0 0 % M
% Asn: 16 8 0 0 0 0 16 0 8 8 8 0 0 0 8 % N
% Pro: 0 0 0 0 16 0 0 8 0 39 0 16 16 8 0 % P
% Gln: 0 0 0 31 0 0 8 0 0 8 8 0 0 0 0 % Q
% Arg: 0 0 0 0 39 8 8 0 0 8 47 47 0 0 0 % R
% Ser: 8 8 24 8 8 8 47 31 8 0 0 0 0 16 0 % S
% Thr: 39 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 8 8 8 0 8 0 0 8 8 0 0 0 0 39 % V
% Trp: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 8 % W
% Tyr: 8 8 0 8 0 0 0 16 0 0 0 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _