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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG1 All Species: 27.27
Human Site: S390 Identified Species: 50
UniProt: P45844 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P45844 NP_004906.3 678 75592 S390 G L R K D S S S M E G C H S F
Chimpanzee Pan troglodytes XP_514918 823 91569 S535 P S E E D S S S M E G C H S F
Rhesus Macaque Macaca mulatta Q5MB13 654 72441 T361 G G E K K K I T V F K E I S Y
Dog Lupus familis XP_544902 661 73719 S373 P S E E D S T S M E G C H S F
Cat Felis silvestris
Mouse Mus musculus Q64343 666 74015 S378 P A E E D S A S M E G C H S F
Rat Rattus norvegicus Q80W57 657 72942 S362 A Q K K K G S S A F R E P V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510754 656 73357 S368 G L R K D S T S T E G C H S F
Chicken Gallus gallus XP_416742 666 74499 S378 P S E E D S S S T E G C H S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001103924 673 75388 S385 P S D E E S S S S E G C H S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10090 687 75654 Q398 N L E K P L E Q P E N G Y T Y
Honey Bee Apis mellifera XP_623409 623 69754 E336 T S L L D S A E S I E Q K V G
Nematode Worm Caenorhab. elegans Q11180 598 66888 Y311 K T F F N Q D Y N A S F W T Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6W5 648 72600 S360 A E L C N A E S H S Y E Y T K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.9 28 94.6 N.A. 95.1 28.3 N.A. 92.6 91 N.A. 84.6 N.A. 30.2 51.9 25.5 N.A.
Protein Similarity: 100 80.9 52.6 95.7 N.A. 96.7 51.1 N.A. 94.4 94.5 N.A. 92.1 N.A. 53.2 70.5 47 N.A.
P-Site Identity: 100 73.3 20 66.6 N.A. 66.6 20 N.A. 86.6 66.6 N.A. 60 N.A. 20 13.3 0 N.A.
P-Site Similarity: 100 80 40 80 N.A. 80 33.3 N.A. 93.3 73.3 N.A. 73.3 N.A. 40 20 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 0 0 8 16 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 54 0 0 0 % C
% Asp: 0 0 8 0 54 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 47 39 8 0 16 8 0 62 8 24 0 0 0 % E
% Phe: 0 0 8 8 0 0 0 0 0 16 0 8 0 0 54 % F
% Gly: 24 8 0 0 0 8 0 0 0 0 54 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 54 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 8 0 0 8 0 0 % I
% Lys: 8 0 8 39 16 8 0 0 0 0 8 0 8 0 8 % K
% Leu: 0 24 16 8 0 8 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 16 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 39 0 0 0 8 0 0 0 8 0 0 0 8 0 0 % P
% Gln: 0 8 0 0 0 8 0 8 0 0 0 8 0 0 8 % Q
% Arg: 0 0 16 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 39 0 0 0 62 39 70 16 8 8 0 0 62 0 % S
% Thr: 8 8 0 0 0 0 16 8 16 0 0 0 0 24 0 % T
% Val: 0 0 0 0 0 0 0 0 8 0 0 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 8 0 16 0 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _