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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG1
All Species:
19.39
Human Site:
S389
Identified Species:
35.56
UniProt:
P45844
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45844
NP_004906.3
678
75592
S389
K
G
L
R
K
D
S
S
S
M
E
G
C
H
S
Chimpanzee
Pan troglodytes
XP_514918
823
91569
S534
R
P
S
E
E
D
S
S
S
M
E
G
C
H
S
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
I360
S
G
G
E
K
K
K
I
T
V
F
K
E
I
S
Dog
Lupus familis
XP_544902
661
73719
T372
R
P
S
E
E
D
S
T
S
M
E
G
C
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64343
666
74015
A377
R
P
A
E
E
D
S
A
S
M
E
G
C
H
S
Rat
Rattus norvegicus
Q80W57
657
72942
S361
V
A
Q
K
K
K
G
S
S
A
F
R
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510754
656
73357
T367
K
G
L
R
K
D
S
T
S
T
E
G
C
H
S
Chicken
Gallus gallus
XP_416742
666
74499
S377
R
P
S
E
E
D
S
S
S
T
E
G
C
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103924
673
75388
S384
R
P
S
D
E
E
S
S
S
S
E
G
C
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
E397
K
N
L
E
K
P
L
E
Q
P
E
N
G
Y
T
Honey Bee
Apis mellifera
XP_623409
623
69754
A335
T
T
S
L
L
D
S
A
E
S
I
E
Q
K
V
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
D310
T
K
T
F
F
N
Q
D
Y
N
A
S
F
W
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6W5
648
72600
E359
K
A
E
L
C
N
A
E
S
H
S
Y
E
Y
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
28
94.6
N.A.
95.1
28.3
N.A.
92.6
91
N.A.
84.6
N.A.
30.2
51.9
25.5
N.A.
Protein Similarity:
100
80.9
52.6
95.7
N.A.
96.7
51.1
N.A.
94.4
94.5
N.A.
92.1
N.A.
53.2
70.5
47
N.A.
P-Site Identity:
100
66.6
20
60
N.A.
60
20
N.A.
86.6
60
N.A.
53.3
N.A.
26.6
13.3
0
N.A.
P-Site Similarity:
100
80
33.3
80
N.A.
80
26.6
N.A.
93.3
73.3
N.A.
73.3
N.A.
40
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
0
0
0
8
16
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
54
0
0
% C
% Asp:
0
0
0
8
0
54
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
47
39
8
0
16
8
0
62
8
24
0
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
16
0
8
0
0
% F
% Gly:
0
24
8
0
0
0
8
0
0
0
0
54
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
54
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% I
% Lys:
31
8
0
8
39
16
8
0
0
0
0
8
0
8
0
% K
% Leu:
0
0
24
16
8
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
16
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
39
0
0
0
8
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
8
0
0
0
8
0
8
0
0
0
8
0
0
% Q
% Arg:
39
0
0
16
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
8
0
39
0
0
0
62
39
70
16
8
8
0
0
62
% S
% Thr:
16
8
8
0
0
0
0
16
8
16
0
0
0
0
24
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _