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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG1
All Species:
18.48
Human Site:
S216
Identified Species:
33.89
UniProt:
P45844
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45844
NP_004906.3
678
75592
S216
C
A
N
T
R
T
G
S
L
S
G
G
Q
R
K
Chimpanzee
Pan troglodytes
XP_514918
823
91569
S373
C
A
N
T
R
T
G
S
L
S
G
G
Q
R
K
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
T202
S
I
G
M
E
L
I
T
D
P
S
I
L
F
L
Dog
Lupus familis
XP_544902
661
73719
S211
C
A
N
T
R
T
G
S
L
S
G
G
Q
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64343
666
74015
S216
C
A
N
T
R
T
G
S
L
S
G
G
Q
R
K
Rat
Rattus norvegicus
Q80W57
657
72942
I205
E
L
I
T
D
P
S
I
L
F
L
D
E
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510754
656
73357
A204
G
G
Q
R
K
R
L
A
I
A
L
E
L
V
N
Chicken
Gallus gallus
XP_416742
666
74499
S216
C
A
N
T
R
T
G
S
L
S
G
G
Q
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001103924
673
75388
H223
C
A
K
T
R
T
S
H
L
S
G
G
Q
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
I231
L
S
K
C
Q
H
T
I
I
G
V
P
G
R
V
Honey Bee
Apis mellifera
XP_623409
623
69754
R179
L
S
G
G
Q
R
K
R
L
S
I
G
L
E
L
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
C154
F
A
S
E
I
L
T
C
P
K
I
L
F
C
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6W5
648
72600
G203
I
G
G
P
L
F
R
G
I
S
G
G
E
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.9
28
94.6
N.A.
95.1
28.3
N.A.
92.6
91
N.A.
84.6
N.A.
30.2
51.9
25.5
N.A.
Protein Similarity:
100
80.9
52.6
95.7
N.A.
96.7
51.1
N.A.
94.4
94.5
N.A.
92.1
N.A.
53.2
70.5
47
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
13.3
N.A.
0
100
N.A.
80
N.A.
6.6
20
6.6
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
20
N.A.
26.6
100
N.A.
80
N.A.
26.6
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
0
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
47
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
8
% D
% Glu:
8
0
0
8
8
0
0
0
0
0
0
8
16
8
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% F
% Gly:
8
16
24
8
0
0
39
8
0
8
54
62
8
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
8
0
8
16
24
0
16
8
0
0
0
% I
% Lys:
0
0
16
0
8
0
8
0
0
8
0
0
0
8
54
% K
% Leu:
16
8
0
0
8
16
8
0
62
0
16
8
24
0
16
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
8
0
8
0
0
8
8
0
8
0
8
0
% P
% Gln:
0
0
8
0
16
0
0
0
0
0
0
0
47
0
0
% Q
% Arg:
0
0
0
8
47
16
8
8
0
0
0
0
0
54
0
% R
% Ser:
8
16
8
0
0
0
16
39
0
62
8
0
0
0
0
% S
% Thr:
0
0
0
54
0
47
16
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _