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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRPPRC
All Species:
16.36
Human Site:
Y393
Identified Species:
40
UniProt:
P42704
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42704
NP_573566.2
1394
157905
Y393
P
V
E
K
L
T
D
Y
C
K
K
L
K
E
V
Chimpanzee
Pan troglodytes
XP_001143797
1394
157780
Y393
P
V
E
K
L
T
D
Y
C
K
K
L
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001107298
1029
116102
I175
Y
C
K
K
L
K
E
I
Q
M
H
S
F
P
L
Dog
Lupus familis
XP_531800
1393
157638
Y393
P
A
E
K
L
K
D
Y
C
K
K
L
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PB66
1392
156596
Y392
P
P
E
K
L
I
D
Y
C
R
R
L
R
D
A
Rat
Rattus norvegicus
Q5SGE0
1392
156634
Y392
P
A
E
K
L
I
D
Y
C
K
R
L
R
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234903
1371
155609
C395
P
L
I
F
I
L
R
C
A
L
E
T
N
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001136064
1436
160823
F415
S
A
E
D
I
V
G
F
C
K
D
L
K
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523596
1412
157245
R440
Q
V
L
E
I
V
R
R
M
Q
Q
E
F
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190098
1315
149084
S389
R
D
M
G
V
E
T
S
S
D
T
L
T
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
60.3
79.6
N.A.
75.2
76.3
N.A.
N.A.
57.3
N.A.
49.2
N.A.
29.2
N.A.
N.A.
33
Protein Similarity:
100
99.7
65.2
88.7
N.A.
86.2
86.5
N.A.
N.A.
73
N.A.
68.6
N.A.
50.3
N.A.
N.A.
53.4
P-Site Identity:
100
100
13.3
80
N.A.
53.3
60
N.A.
N.A.
6.6
N.A.
33.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
33.3
80
N.A.
80
80
N.A.
N.A.
33.3
N.A.
60
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
0
0
0
0
10
0
0
0
0
0
20
% A
% Cys:
0
10
0
0
0
0
0
10
60
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
50
0
0
10
10
0
0
30
0
% D
% Glu:
0
0
60
10
0
10
10
0
0
0
10
10
0
30
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
0
0
20
0
10
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
30
20
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
60
0
20
0
0
0
50
30
0
40
20
0
% K
% Leu:
0
10
10
0
60
10
0
0
0
10
0
70
0
0
20
% L
% Met:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
60
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
20
10
0
10
20
0
20
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
10
0
0
10
0
10
20
% S
% Thr:
0
0
0
0
0
20
10
0
0
0
10
10
10
0
0
% T
% Val:
0
30
0
0
10
20
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _