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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRPPRC
All Species:
21.52
Human Site:
T225
Identified Species:
52.59
UniProt:
P42704
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42704
NP_573566.2
1394
157905
T225
K
I
L
G
F
M
K
T
K
D
L
P
V
T
E
Chimpanzee
Pan troglodytes
XP_001143797
1394
157780
T225
K
I
L
G
F
M
K
T
K
D
L
P
V
T
E
Rhesus Macaque
Macaca mulatta
XP_001107298
1029
116102
T10
L
D
N
S
V
R
R
T
G
R
I
P
K
M
L
Dog
Lupus familis
XP_531800
1393
157638
T225
K
I
L
G
F
M
K
T
K
D
L
P
V
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PB66
1392
156596
T224
K
I
L
G
F
M
K
T
K
D
L
P
I
T
E
Rat
Rattus norvegicus
Q5SGE0
1392
156634
T224
K
I
L
G
F
M
K
T
R
D
L
P
I
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234903
1371
155609
S228
L
V
K
G
H
A
R
S
G
D
I
K
S
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001136064
1436
160823
N244
A
I
L
G
F
M
K
N
K
D
L
P
I
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523596
1412
157245
Q273
E
T
L
A
E
C
E
Q
K
E
I
I
L
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190098
1315
149084
C224
D
T
Y
T
A
L
M
C
A
Y
A
E
K
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
60.3
79.6
N.A.
75.2
76.3
N.A.
N.A.
57.3
N.A.
49.2
N.A.
29.2
N.A.
N.A.
33
Protein Similarity:
100
99.7
65.2
88.7
N.A.
86.2
86.5
N.A.
N.A.
73
N.A.
68.6
N.A.
50.3
N.A.
N.A.
53.4
P-Site Identity:
100
100
13.3
100
N.A.
93.3
86.6
N.A.
N.A.
20
N.A.
80
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
46.6
N.A.
86.6
N.A.
53.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
10
0
0
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
70
0
0
0
0
10
% D
% Glu:
10
0
0
0
10
0
10
0
0
10
0
10
0
0
80
% E
% Phe:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
0
20
0
0
0
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
0
0
0
0
0
0
30
10
30
0
0
% I
% Lys:
50
0
10
0
0
0
60
0
60
0
0
10
20
0
0
% K
% Leu:
20
0
70
0
0
10
0
0
0
0
60
0
10
10
10
% L
% Met:
0
0
0
0
0
60
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
20
0
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% S
% Thr:
0
20
0
10
0
0
0
60
0
0
0
0
0
60
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _