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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
29.7
Human Site:
Y368
Identified Species:
54.44
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
Y368
R
S
D
M
I
C
G
Y
A
C
L
K
G
T
A
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Y204
Y
S
T
A
P
G
Y
Y
S
W
R
N
S
K
D
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
K348
E
K
D
F
I
A
F
K
S
S
T
P
H
N
V
Dog
Lupus familis
XP_848601
452
50347
Y368
R
S
D
M
I
C
G
Y
A
C
L
R
G
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
Y368
R
S
D
M
I
C
G
Y
A
C
L
K
G
N
A
Rat
Rattus norvegicus
P55215
452
50709
Y368
R
S
D
M
I
C
G
Y
A
C
L
K
G
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
Y686
R
S
D
M
I
C
G
Y
A
C
L
K
G
T
A
Chicken
Gallus gallus
Q98943
424
47941
Y339
R
S
D
M
I
C
G
Y
A
C
L
K
G
T
A
Frog
Xenopus laevis
P55867
382
43370
S309
D
S
I
C
F
Y
S
S
T
P
D
T
A
S
W
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
F350
R
S
D
M
I
C
G
F
A
T
L
K
G
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
S265
W
R
N
T
T
R
G
S
W
F
M
Q
S
L
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
Y419
Q
A
D
I
L
I
A
Y
A
T
T
A
Q
Y
V
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
Y359
Q
S
D
M
L
L
A
Y
A
T
V
P
G
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
13.3
13.3
93.3
N.A.
93.3
93.3
N.A.
100
100
6.6
86.6
N.A.
6.6
N.A.
20
40
P-Site Similarity:
100
20
20
100
N.A.
93.3
93.3
N.A.
100
100
13.3
93.3
N.A.
26.6
N.A.
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
16
0
70
0
0
8
8
0
54
% A
% Cys:
0
0
0
8
0
54
0
0
0
47
0
0
0
0
8
% C
% Asp:
8
0
77
0
0
0
0
0
0
0
8
0
0
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
8
0
8
8
0
8
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
62
0
0
0
0
0
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
8
8
62
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
8
0
0
0
47
0
8
0
% K
% Leu:
0
0
0
0
16
8
0
0
0
0
54
0
0
8
0
% L
% Met:
0
0
0
62
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
8
0
24
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
8
0
16
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
54
8
0
0
0
8
0
0
0
0
8
8
0
0
0
% R
% Ser:
0
77
0
0
0
0
8
16
16
8
0
0
16
8
0
% S
% Thr:
0
0
8
8
8
0
0
0
8
24
16
8
0
39
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
24
% V
% Trp:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% W
% Tyr:
8
0
0
0
0
8
8
70
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _