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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP2
All Species:
17.88
Human Site:
Y184
Identified Species:
32.78
UniProt:
P42575
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42575
NP_116764.2
452
50685
Y184
K
P
C
T
P
E
F
Y
Q
T
H
F
Q
L
A
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
S36
S
G
I
S
L
D
N
S
Y
K
M
D
Y
P
E
Rhesus Macaque
Macaca mulatta
Q153Z0
421
47740
K162
H
F
R
E
L
K
T
K
R
A
D
E
I
Y
P
Dog
Lupus familis
XP_848601
452
50347
Y184
K
P
C
T
P
E
F
Y
Q
T
H
Y
Q
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
Y184
K
P
C
T
P
E
F
Y
Q
A
H
Y
Q
L
A
Rat
Rattus norvegicus
P55215
452
50709
Y184
K
P
C
T
P
E
F
Y
Q
A
H
Y
Q
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506482
767
84465
Y502
K
P
C
T
P
E
F
Y
R
V
H
H
H
L
A
Chicken
Gallus gallus
Q98943
424
47941
H160
E
F
Y
R
D
H
Q
H
L
A
Y
K
L
I
S
Frog
Xenopus laevis
P55867
382
43370
K141
V
R
E
R
E
G
R
K
R
L
A
L
I
I
C
Zebra Danio
Brachydanio rerio
NP_001036160
435
49559
R162
R
P
Q
A
Y
P
M
R
S
C
P
R
G
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O01382
339
37345
L97
H
K
N
R
G
M
A
L
I
F
N
H
E
H
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
T224
M
N
F
V
D
A
P
T
I
S
R
V
F
D
E
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
T184
T
M
P
P
R
R
G
T
D
I
D
C
R
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
22.5
89.8
N.A.
89.5
89.5
N.A.
47.9
67
22.1
49.7
N.A.
25
N.A.
25.2
27.6
Protein Similarity:
100
36.2
42
92.6
N.A.
93.3
93.8
N.A.
51.2
76.9
40.9
64.3
N.A.
40.7
N.A.
42.3
47.5
P-Site Identity:
100
0
0
93.3
N.A.
86.6
86.6
N.A.
73.3
0
0
20
N.A.
0
N.A.
0
0
P-Site Similarity:
100
13.3
13.3
100
N.A.
93.3
93.3
N.A.
80
33.3
13.3
26.6
N.A.
13.3
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
0
0
31
8
0
0
0
47
% A
% Cys:
0
0
39
0
0
0
0
0
0
8
0
8
0
0
8
% C
% Asp:
0
0
0
0
16
8
0
0
8
0
16
8
0
8
0
% D
% Glu:
8
0
8
8
8
39
0
0
0
0
0
8
8
0
16
% E
% Phe:
0
16
8
0
0
0
39
0
0
8
0
8
8
0
8
% F
% Gly:
0
8
0
0
8
8
8
0
0
0
0
0
8
0
0
% G
% His:
16
0
0
0
0
8
0
8
0
0
39
16
8
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
16
8
0
0
16
16
0
% I
% Lys:
39
8
0
0
0
8
0
16
0
8
0
8
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
8
8
8
0
8
8
47
8
% L
% Met:
8
8
0
0
0
8
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
0
0
8
0
0
8
0
% N
% Pro:
0
47
8
8
39
8
8
0
0
0
8
0
0
8
8
% P
% Gln:
0
0
8
0
0
0
8
0
31
0
0
0
31
0
0
% Q
% Arg:
8
8
8
24
8
8
8
8
24
0
8
8
8
0
0
% R
% Ser:
8
0
0
8
0
0
0
8
8
8
0
0
0
0
8
% S
% Thr:
8
0
0
39
0
0
8
16
0
16
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
39
8
0
8
24
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _