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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
9.39
Human Site:
S764
Identified Species:
20.67
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
S764
F
E
E
T
S
V
K
S
E
D
E
P
P
A
L
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
S764
F
E
E
T
S
V
K
S
E
D
E
P
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
P886
Q
D
T
P
A
L
P
P
K
K
P
A
P
P
R
Dog
Lupus familis
XP_532580
889
97932
G754
L
E
E
V
S
V
K
G
E
D
V
P
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
S766
L
E
E
T
A
S
K
S
E
D
V
P
P
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
N790
F
E
E
P
P
A
K
N
E
D
I
P
P
A
L
Frog
Xenopus laevis
O42287
1270
143652
T883
A
F
T
P
A
T
V
T
G
S
S
P
S
P
V
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
V856
A
P
G
G
T
T
V
V
A
N
S
D
P
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
E803
E
K
N
M
L
Q
P
E
P
T
L
N
R
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
D930
F
A
G
S
T
N
T
D
D
P
F
K
G
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
I1165
Q
P
T
S
S
L
E
I
H
T
E
Q
V
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
6.6
73.3
N.A.
73.3
N.A.
N.A.
N.A.
66.6
6.6
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
33.3
73.3
N.A.
80
N.A.
N.A.
N.A.
73.3
26.6
20
N.A.
N.A.
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
28
10
0
0
10
0
0
10
0
46
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
10
46
0
10
0
10
10
% D
% Glu:
10
46
46
0
0
0
10
10
46
0
28
0
0
0
0
% E
% Phe:
37
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
19
10
0
0
0
10
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
46
0
10
10
0
10
0
0
19
% K
% Leu:
19
0
0
0
10
19
0
0
0
0
10
0
0
0
46
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
10
0
10
0
10
0
0
0
% N
% Pro:
0
19
0
28
10
0
19
10
10
10
10
55
64
19
0
% P
% Gln:
19
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% R
% Ser:
0
0
0
19
37
10
0
28
0
10
19
0
10
10
0
% S
% Thr:
0
0
28
28
19
19
10
10
0
19
0
0
0
10
0
% T
% Val:
0
0
0
10
0
28
19
10
0
0
19
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _