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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
11.82
Human Site:
S662
Identified Species:
26
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
S662
S
D
C
F
F
R
Q
S
T
D
P
F
A
T
S
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
S662
S
D
C
F
F
R
Q
S
T
D
P
F
A
T
S
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
K784
S
A
T
D
D
F
F
K
K
Q
T
K
N
D
P
Dog
Lupus familis
XP_532580
889
97932
T652
C
F
F
K
Q
S
S
T
D
P
F
A
T
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
T664
C
F
F
K
Q
T
S
T
D
P
F
T
T
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
T688
C
F
F
K
Q
S
S
T
D
P
F
V
T
A
G
Frog
Xenopus laevis
O42287
1270
143652
G781
G
E
L
K
G
K
T
G
W
F
P
A
N
Y
A
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
S754
A
D
N
F
F
K
Q
S
S
G
S
F
P
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
T701
A
P
P
T
P
S
P
T
P
D
P
F
A
N
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
D828
S
S
S
P
G
S
T
D
P
F
G
G
S
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
A1063
W
E
A
T
P
A
T
A
S
T
D
V
L
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
0
6.6
40
N.A.
N.A.
26.6
N.A.
13.3
P-Site Similarity:
100
100
6.6
20
N.A.
20
N.A.
N.A.
N.A.
6.6
26.6
66.6
N.A.
N.A.
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
0
0
10
0
10
0
0
0
19
28
10
28
% A
% Cys:
28
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
0
10
10
0
0
10
28
28
10
0
0
10
0
% D
% Glu:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
28
28
28
28
10
10
0
0
19
28
37
0
0
0
% F
% Gly:
10
0
0
0
19
0
0
10
0
10
10
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
37
0
19
0
10
10
0
0
10
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
19
10
10
% N
% Pro:
0
10
10
10
19
0
10
0
19
28
37
0
10
0
10
% P
% Gln:
0
0
0
0
28
0
28
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
10
% R
% Ser:
37
10
10
0
0
37
28
28
19
0
10
0
10
37
37
% S
% Thr:
0
0
10
19
0
10
28
37
19
10
10
10
28
28
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _