KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3CB
All Species:
30.3
Human Site:
T744
Identified Species:
47.62
UniProt:
P42338
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42338
NP_006210.1
1070
122762
T744
K
G
K
E
A
M
H
T
C
L
K
Q
S
A
Y
Chimpanzee
Pan troglodytes
XP_001160550
1044
119347
L717
Q
T
K
E
L
M
H
L
C
M
R
Q
E
A
Y
Rhesus Macaque
Macaca mulatta
XP_001113960
1070
122801
T744
K
G
K
E
A
M
H
T
C
L
K
Q
S
A
Y
Dog
Lupus familis
XP_534280
1070
122787
T744
K
G
K
E
A
M
H
T
C
L
K
Q
N
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTI9
1064
121735
T738
K
G
K
E
A
M
H
T
C
L
K
Q
S
A
Y
Rat
Rattus norvegicus
Q9Z1L0
1070
122589
T744
K
G
K
E
A
M
H
T
C
L
K
Q
S
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516423
1162
131381
S856
N
K
L
K
T
L
N
S
L
M
K
L
N
A
V
Chicken
Gallus gallus
NP_001026482
1066
122000
T740
K
G
K
D
A
M
H
T
C
L
K
Q
N
A
Y
Frog
Xenopus laevis
Q6AZN6
886
101139
M582
L
L
G
D
N
E
K
M
N
L
S
E
F
E
P
Zebra Danio
Brachydanio rerio
XP_001923257
1022
117051
S698
H
L
K
E
A
M
M
S
C
L
R
Q
T
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623897
1071
123316
E741
A
A
L
Q
G
F
Q
E
F
I
Q
E
P
H
C
Nematode Worm
Caenorhab. elegans
Q94125
1182
136855
S831
K
L
R
D
E
L
R
S
I
S
H
K
M
E
N
Sea Urchin
Strong. purpuratus
XP_001201471
1049
120959
K723
E
I
R
D
M
M
Q
K
V
L
Q
Q
D
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
E510
L
L
G
G
L
L
S
E
L
T
Y
F
E
E
P
Baker's Yeast
Sacchar. cerevisiae
P22543
875
100903
R571
H
L
L
E
T
K
V
R
P
L
V
K
V
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
99.6
97.2
N.A.
95.2
95.8
N.A.
81.1
86.6
23.6
65.5
N.A.
N.A.
46.6
26.4
42.9
Protein Similarity:
100
72.9
99.9
98.8
N.A.
97
97.8
N.A.
85.3
93.6
41.3
79.7
N.A.
N.A.
65.6
47.8
63.6
P-Site Identity:
100
53.3
100
93.3
N.A.
100
100
N.A.
13.3
86.6
6.6
46.6
N.A.
N.A.
0
6.6
26.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
53.3
100
20
73.3
N.A.
N.A.
26.6
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
41.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
47
0
0
0
0
0
0
0
0
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
7
% C
% Asp:
0
0
0
27
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
7
0
0
54
7
7
0
14
0
0
0
14
14
20
0
% E
% Phe:
0
0
0
0
0
7
0
0
7
0
0
7
7
0
7
% F
% Gly:
0
40
14
7
7
0
0
0
0
0
0
0
0
7
0
% G
% His:
14
0
0
0
0
0
47
0
0
0
7
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
7
0
0
0
0
0
% I
% Lys:
47
7
54
7
0
7
7
7
0
0
47
14
0
0
0
% K
% Leu:
14
34
20
0
14
20
0
7
14
67
0
7
0
0
0
% L
% Met:
0
0
0
0
7
60
7
7
0
14
0
0
7
0
0
% M
% Asn:
7
0
0
0
7
0
7
0
7
0
0
0
20
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
20
% P
% Gln:
7
0
0
7
0
0
14
0
0
0
14
60
0
0
0
% Q
% Arg:
0
0
14
0
0
0
7
7
0
0
14
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
7
20
0
7
7
0
27
7
0
% S
% Thr:
0
7
0
0
14
0
0
40
0
7
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
7
0
7
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _