KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIV2L2
All Species:
22.73
Human Site:
Y643
Identified Species:
45.45
UniProt:
P42285
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42285
NP_056175.3
1042
117805
Y643
L
G
K
E
I
E
E
Y
I
H
K
P
K
Y
C
Chimpanzee
Pan troglodytes
XP_001145794
1042
117753
Y643
L
G
K
E
I
E
E
Y
I
H
K
P
K
Y
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849676
1042
117789
Y643
L
G
K
E
I
E
E
Y
V
H
K
P
K
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZU3
1040
117618
Y641
L
G
K
E
I
E
E
Y
I
H
K
P
K
Y
C
Rat
Rattus norvegicus
NP_001029265
1042
117927
Y643
L
G
K
E
I
E
E
Y
I
H
K
P
K
Y
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012962
1029
116029
Y630
L
G
K
E
I
E
E
Y
I
H
K
P
K
Y
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999933
1034
116547
F636
L
G
K
E
I
E
E
F
I
H
K
P
R
Y
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524929
1055
118907
W659
H
G
K
Q
F
R
Q
W
I
T
K
P
Q
Y
L
Honey Bee
Apis mellifera
XP_624031
1022
117163
F629
L
S
T
E
F
R
C
F
L
T
K
P
E
Y
L
Nematode Worm
Caenorhab. elegans
Q23223
1026
116352
I630
T
R
Q
R
I
I
Q
I
Q
R
E
P
K
Y
I
Sea Urchin
Strong. purpuratus
XP_001180500
1024
116147
F624
L
A
K
E
I
Q
A
F
I
T
K
P
K
Y
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47047
1073
122036
V663
Y
R
E
D
V
R
Q
V
V
T
H
P
A
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.8
N.A.
97.5
97.7
N.A.
N.A.
91.1
N.A.
85.1
N.A.
62.1
65.3
51.3
73.8
Protein Similarity:
100
99.9
N.A.
99.5
N.A.
99
99.1
N.A.
N.A.
94.3
N.A.
91.9
N.A.
76.7
80.2
67.1
86.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
100
N.A.
86.6
N.A.
40
33.3
26.6
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
66.6
53.3
46.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
9
0
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
67
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
75
0
59
59
0
0
0
9
0
9
0
0
% E
% Phe:
0
0
0
0
17
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
59
9
0
0
0
0
% H
% Ile:
0
0
0
0
75
9
0
9
67
0
0
0
0
0
9
% I
% Lys:
0
0
75
0
0
0
0
0
0
0
84
0
67
0
0
% K
% Leu:
75
0
0
0
0
0
0
0
9
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% P
% Gln:
0
0
9
9
0
9
25
0
9
0
0
0
9
0
0
% Q
% Arg:
0
17
0
9
0
25
0
0
0
9
0
0
9
0
0
% R
% Ser:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
0
0
0
0
0
34
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
9
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
50
0
0
0
0
0
92
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _