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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: APOBEC1 All Species: 11.82
Human Site: Y40 Identified Species: 28.89
UniProt: P41238 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P41238 NP_001635.2 236 28192 Y40 R K E A C L L Y E I K W G M S
Chimpanzee Pan troglodytes Q7YR24 384 46070 P44 Y E V K T K G P S R P P L D A
Rhesus Macaque Macaca mulatta Q7YR23 370 43595 Y57 K V Y S K A K Y H P E M R F L
Dog Lupus familis XP_543826 251 29870 Y55 R K E T C L L Y E I Q W G T S
Cat Felis silvestris
Mouse Mus musculus P51908 229 27503 Y40 R K E T C L L Y E I N W G G R
Rat Rattus norvegicus P38483 229 27256 Y40 R K E T C L L Y E I N W G G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516174 195 23517
Chicken Gallus gallus XP_416483 198 23812 L10 S L L M K R K L F L Y N F K N
Frog Xenopus laevis NP_001089181 201 24285 F13 M L L K R N K F I Y H Y K N L
Zebra Danio Brachydanio rerio NP_001008403 210 24603 V22 F I F H Y K N V R W A R G R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.1 20.5 70.9 N.A. 68.6 67.3 N.A. 23.7 26.6 26.2 27.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 34.6 32.1 77.6 N.A. 79.6 77.5 N.A. 44 44.9 43.2 47.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 80 N.A. 73.3 73.3 N.A. 0 0 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 26.6 86.6 N.A. 73.3 73.3 N.A. 0 13.3 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 10 0 0 0 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 40 0 0 0 0 0 40 0 10 0 0 0 0 % E
% Phe: 10 0 10 0 0 0 0 10 10 0 0 0 10 10 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 50 20 0 % G
% His: 0 0 0 10 0 0 0 0 10 0 10 0 0 0 10 % H
% Ile: 0 10 0 0 0 0 0 0 10 40 0 0 0 0 0 % I
% Lys: 10 40 0 20 20 20 30 0 0 0 10 0 10 10 0 % K
% Leu: 0 20 20 0 0 40 40 10 0 10 0 0 10 0 20 % L
% Met: 10 0 0 10 0 0 0 0 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 0 0 10 10 0 0 0 20 10 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 10 0 10 10 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 40 0 0 0 10 10 0 0 10 10 0 10 10 10 20 % R
% Ser: 10 0 0 10 0 0 0 0 10 0 0 0 0 0 20 % S
% Thr: 0 0 0 30 10 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 10 10 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 40 0 0 0 % W
% Tyr: 10 0 10 0 10 0 0 50 0 10 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _