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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNF4A
All Species:
20.91
Human Site:
S16
Identified Species:
38.33
UniProt:
P41235
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41235
NP_849180.1
474
52785
S16
D
M
D
M
A
D
Y
S
A
A
L
D
P
A
Y
Chimpanzee
Pan troglodytes
XP_514664
468
51900
L25
E
F
E
N
V
Q
V
L
T
M
G
N
D
F
V
Rhesus Macaque
Macaca mulatta
XP_001110097
452
49945
L19
H
P
A
L
V
P
C
L
T
P
F
S
P
G
A
Dog
Lupus familis
XP_852731
474
52640
S16
D
M
D
M
A
D
Y
S
A
A
L
D
P
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
P49698
474
52665
S16
G
M
D
M
A
D
Y
S
A
A
L
D
P
A
Y
Rat
Rattus norvegicus
P22449
474
52693
S16
D
M
D
M
A
D
Y
S
A
A
L
D
P
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507309
419
46844
L12
K
A
L
V
D
M
E
L
A
D
Y
S
A
A
L
Chicken
Gallus gallus
NP_001026026
454
50607
T16
A
L
D
P
A
Y
T
T
L
E
F
E
N
M
Q
Frog
Xenopus laevis
Q91766
464
51948
T16
D
M
D
M
A
D
Y
T
E
A
L
D
P
A
Y
Zebra Danio
Brachydanio rerio
A2T929
430
47452
S16
T
S
L
G
P
S
G
S
L
H
S
P
I
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49866
666
71882
S60
A
G
S
A
G
G
G
S
A
S
S
G
S
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44960
369
41820
Sea Urchin
Strong. purpuratus
XP_780389
468
51669
T16
S
S
S
S
C
S
P
T
E
P
D
L
N
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
90.9
98.3
N.A.
95.7
96.1
N.A.
79.5
84.1
80.8
33.7
N.A.
42.4
N.A.
33.9
57.1
Protein Similarity:
100
82.9
91.9
99.1
N.A.
97
97.4
N.A.
84.8
89.8
89.6
51.4
N.A.
54.5
N.A.
49.5
72.3
P-Site Identity:
100
0
6.6
100
N.A.
93.3
100
N.A.
13.3
13.3
86.6
6.6
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
20
13.3
100
N.A.
93.3
100
N.A.
20
33.3
93.3
13.3
N.A.
20
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
8
47
0
0
0
47
39
0
0
8
47
8
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
47
0
8
39
0
0
0
8
8
39
8
0
0
% D
% Glu:
8
0
8
0
0
0
8
0
16
8
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
16
0
0
8
0
% F
% Gly:
8
8
0
8
8
8
16
0
0
0
8
8
0
16
0
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
16
8
0
0
0
24
16
0
39
8
0
0
8
% L
% Met:
0
39
0
39
0
8
0
0
0
8
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
16
8
8
% N
% Pro:
0
8
0
8
8
8
8
0
0
16
0
8
47
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
16
8
0
16
0
47
0
8
16
16
8
8
0
% S
% Thr:
8
0
0
0
0
0
8
24
16
0
0
0
0
0
8
% T
% Val:
0
0
0
8
16
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
39
0
0
0
8
0
0
0
39
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _