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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPRK1
All Species:
26.67
Human Site:
S356
Identified Species:
65.19
UniProt:
P41145
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41145
NP_000903.2
380
42645
S356
K
M
R
M
E
R
Q
S
T
S
R
V
R
N
T
Chimpanzee
Pan troglodytes
Q5IS39
401
44883
S366
S
N
I
E
Q
Q
N
S
T
R
I
R
Q
N
T
Rhesus Macaque
Macaca mulatta
Q9MYW9
400
44791
S365
S
N
I
E
Q
Q
N
S
T
R
I
R
Q
N
T
Dog
Lupus familis
XP_544080
380
42713
S356
K
M
R
M
E
R
Q
S
T
S
R
V
R
N
T
Cat
Felis silvestris
Mouse
Mus musculus
P33534
380
42634
S356
K
M
R
M
E
R
Q
S
T
N
R
V
R
N
T
Rat
Rattus norvegicus
P34975
380
42670
S356
K
M
R
M
E
R
Q
S
T
N
R
V
R
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514649
423
48636
S399
K
S
R
M
D
R
Q
S
T
S
R
I
R
N
T
Chicken
Gallus gallus
XP_426087
381
43124
S357
K
M
R
M
D
R
Q
S
T
S
R
V
R
N
T
Frog
Xenopus laevis
NP_001089156
362
40659
M337
A
F
R
P
E
L
Q
M
S
N
R
M
C
S
I
Zebra Danio
Brachydanio rerio
NP_878306
377
42288
G350
R
T
A
G
D
G
R
G
V
S
R
V
R
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.1
57
92.8
N.A.
93.6
94.2
N.A.
70.9
85.5
57.3
69.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71
71.5
96.3
N.A.
97.6
97.6
N.A.
77.5
90.2
71.5
80.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
26.6
100
N.A.
93.3
93.3
N.A.
80
93.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
46.6
100
N.A.
100
100
N.A.
93.3
100
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
20
50
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
20
10
0
0
10
% I
% Lys:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
50
0
60
0
0
0
10
0
0
0
10
0
0
0
% M
% Asn:
0
20
0
0
0
0
20
0
0
30
0
0
0
80
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
20
20
70
0
0
0
0
0
20
0
0
% Q
% Arg:
10
0
70
0
0
60
10
0
0
20
80
20
70
0
0
% R
% Ser:
20
10
0
0
0
0
0
80
10
50
0
0
0
20
0
% S
% Thr:
0
10
0
0
0
0
0
0
80
0
0
0
0
0
90
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _