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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP8
All Species:
36.97
Human Site:
T33
Identified Species:
62.56
UniProt:
P40818
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40818
NP_001122082.1
1118
127523
T33
V
K
P
E
K
I
S
T
K
S
Y
V
H
S
A
Chimpanzee
Pan troglodytes
XP_001168710
1118
127532
T33
V
K
P
E
K
I
S
T
K
S
Y
V
H
S
A
Rhesus Macaque
Macaca mulatta
XP_001114466
1118
127660
T33
V
K
P
E
K
I
S
T
K
S
Y
V
H
S
A
Dog
Lupus familis
XP_535474
1116
127497
T33
V
K
P
E
K
I
S
T
K
N
Y
V
Q
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80U87
1080
122592
T33
V
K
P
E
K
T
S
T
K
N
Y
I
H
S
A
Rat
Rattus norvegicus
NP_001099972
1081
122532
T33
V
K
P
E
K
T
S
T
K
N
Y
I
H
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507996
1116
126304
T33
V
K
P
E
K
I
S
T
K
S
Y
V
Q
S
A
Chicken
Gallus gallus
XP_413830
1116
127997
T34
K
H
E
K
T
N
S
T
K
S
Y
V
Q
S
A
Frog
Xenopus laevis
NP_001080551
1063
120542
T33
V
K
P
D
K
T
S
T
K
S
Y
V
S
S
A
Zebra Danio
Brachydanio rerio
XP_693811
1099
124389
T33
I
K
P
D
K
S
S
T
R
H
Y
V
Q
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650948
896
102648
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784858
1187
131804
Y35
K
G
Q
T
S
K
I
Y
A
R
S
A
N
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Y01
910
102631
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
91.8
N.A.
81.8
81.9
N.A.
76.9
74.4
59.9
53.5
N.A.
31.4
N.A.
N.A.
39
Protein Similarity:
100
99.7
99.1
95.3
N.A.
88
87.7
N.A.
87
84.8
74.2
69.5
N.A.
47.7
N.A.
N.A.
56.3
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
93.3
53.3
80
60
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
60
86.6
80
N.A.
0
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
72
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
50
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
36
0
0
% H
% Ile:
8
0
0
0
0
36
8
0
0
0
0
15
0
0
0
% I
% Lys:
15
65
0
8
65
8
0
0
65
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
22
0
0
8
0
0
% N
% Pro:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
29
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
72
0
0
43
8
0
8
72
0
% S
% Thr:
0
0
0
8
8
22
0
72
0
0
0
0
0
8
0
% T
% Val:
58
0
0
0
0
0
0
0
0
0
0
58
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
72
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _