KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP8
All Species:
16.67
Human Site:
S555
Identified Species:
28.21
UniProt:
P40818
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40818
NP_001122082.1
1118
127523
S555
I
T
G
V
K
R
Q
S
K
S
E
H
E
T
S
Chimpanzee
Pan troglodytes
XP_001168710
1118
127532
S555
I
T
G
V
K
R
Q
S
K
S
E
H
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001114466
1118
127660
S555
I
T
G
V
K
R
Q
S
K
S
E
H
E
T
S
Dog
Lupus familis
XP_535474
1116
127497
S554
I
T
G
V
K
R
Q
S
K
S
E
H
E
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80U87
1080
122592
K525
G
Q
E
K
K
D
S
K
Q
T
K
T
E
D
R
Rat
Rattus norvegicus
NP_001099972
1081
122532
G518
N
Q
H
K
A
K
D
G
Q
E
K
R
D
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507996
1116
126304
S553
Q
N
Q
S
D
H
E
S
A
E
A
E
K
S
D
Chicken
Gallus gallus
XP_413830
1116
127997
K553
K
E
A
I
E
A
K
K
Q
N
K
N
E
P
E
Frog
Xenopus laevis
NP_001080551
1063
120542
E527
H
P
F
A
A
G
K
E
P
S
E
P
K
R
L
Zebra Danio
Brachydanio rerio
XP_693811
1099
124389
R518
K
R
E
Q
E
Q
R
R
R
A
Q
E
Q
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650948
896
102648
E372
E
Q
N
D
E
Q
L
E
K
A
S
K
M
W
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784858
1187
131804
N590
K
T
S
S
P
S
H
N
A
Q
S
P
S
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Y01
910
102631
F386
L
A
R
F
A
P
Q
F
S
G
Y
N
Q
H
D
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
S402
N
D
H
V
L
K
R
S
S
S
F
K
K
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
91.8
N.A.
81.8
81.9
N.A.
76.9
74.4
59.9
53.5
N.A.
31.4
N.A.
N.A.
39
Protein Similarity:
100
99.7
99.1
95.3
N.A.
88
87.7
N.A.
87
84.8
74.2
69.5
N.A.
47.7
N.A.
N.A.
56.3
P-Site Identity:
100
100
100
93.3
N.A.
13.3
0
N.A.
6.6
6.6
13.3
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
26.6
53.3
26.6
46.6
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
22
8
0
0
15
15
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
8
8
0
0
0
0
0
8
8
15
% D
% Glu:
8
8
15
0
22
0
8
15
0
15
36
15
43
8
8
% E
% Phe:
0
0
8
8
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
8
0
29
0
0
8
0
8
0
8
0
0
0
0
0
% G
% His:
8
0
15
0
0
8
8
0
0
0
0
29
0
8
0
% H
% Ile:
29
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
22
0
0
15
36
15
15
15
36
0
22
15
22
0
22
% K
% Leu:
8
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
15
8
8
0
0
0
0
8
0
8
0
15
0
0
0
% N
% Pro:
0
8
0
0
8
8
0
0
8
0
0
15
0
15
0
% P
% Gln:
8
22
8
8
0
15
36
0
22
8
8
0
15
0
0
% Q
% Arg:
0
8
8
0
0
29
15
8
8
0
0
8
0
8
8
% R
% Ser:
0
0
8
15
0
8
8
43
15
43
15
0
8
15
22
% S
% Thr:
0
36
0
0
0
0
0
0
0
8
0
8
0
29
8
% T
% Val:
0
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _