KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP8
All Species:
17.27
Human Site:
S445
Identified Species:
29.23
UniProt:
P40818
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40818
NP_001122082.1
1118
127523
S445
G
K
V
I
P
D
R
S
T
K
P
V
V
F
S
Chimpanzee
Pan troglodytes
XP_001168710
1118
127532
S445
G
K
V
I
P
D
R
S
T
K
P
V
V
F
S
Rhesus Macaque
Macaca mulatta
XP_001114466
1118
127660
S445
G
K
V
I
P
D
R
S
T
K
P
V
V
F
S
Dog
Lupus familis
XP_535474
1116
127497
S445
G
K
V
V
P
D
R
S
T
K
P
V
F
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80U87
1080
122592
P445
R
S
T
K
P
V
F
P
S
P
T
T
M
L
T
Rat
Rattus norvegicus
NP_001099972
1081
122532
S439
G
R
V
L
S
D
R
S
T
K
P
V
F
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507996
1116
126304
P441
V
P
D
R
S
K
K
P
A
F
D
P
T
A
V
Chicken
Gallus gallus
XP_413830
1116
127997
T445
R
V
V
P
D
R
S
T
K
P
L
L
D
A
K
Frog
Xenopus laevis
NP_001080551
1063
120542
P441
M
L
N
G
K
P
I
P
D
R
S
T
K
P
S
Zebra Danio
Brachydanio rerio
XP_693811
1099
124389
Q438
A
S
P
R
H
T
P
Q
V
D
R
S
K
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650948
896
102648
I293
P
Q
Q
N
N
N
D
I
E
T
I
D
D
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784858
1187
131804
A433
N
L
E
S
K
T
I
A
R
T
P
D
L
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Y01
910
102631
N307
G
G
L
A
G
L
S
N
L
G
N
T
C
F
M
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
N323
F
P
G
W
L
K
S
N
Y
G
R
Q
V
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
91.8
N.A.
81.8
81.9
N.A.
76.9
74.4
59.9
53.5
N.A.
31.4
N.A.
N.A.
39
Protein Similarity:
100
99.7
99.1
95.3
N.A.
88
87.7
N.A.
87
84.8
74.2
69.5
N.A.
47.7
N.A.
N.A.
56.3
P-Site Identity:
100
100
100
73.3
N.A.
6.6
66.6
N.A.
0
6.6
6.6
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
26.6
80
N.A.
6.6
20
13.3
0
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
8
0
0
0
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
8
36
8
0
8
8
8
15
15
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
8
0
0
8
0
0
15
29
0
% F
% Gly:
43
8
8
8
8
0
0
0
0
15
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
22
0
0
15
8
0
0
8
0
0
8
0
% I
% Lys:
0
29
0
8
15
15
8
0
8
36
0
0
15
8
15
% K
% Leu:
0
15
8
8
8
8
0
0
8
0
8
8
8
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
8
0
8
8
8
8
0
15
0
0
8
0
0
0
0
% N
% Pro:
8
15
8
8
36
8
8
22
0
15
43
8
0
15
15
% P
% Gln:
0
8
8
0
0
0
0
8
0
0
0
8
0
0
0
% Q
% Arg:
15
8
0
15
0
8
36
0
8
8
15
0
0
0
0
% R
% Ser:
0
15
0
8
15
0
22
36
8
0
8
8
0
8
43
% S
% Thr:
0
0
8
0
0
15
0
8
36
15
8
22
8
8
8
% T
% Val:
8
8
43
8
0
8
0
0
8
0
0
36
29
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _