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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP8
All Species:
16.06
Human Site:
S355
Identified Species:
27.18
UniProt:
P40818
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40818
NP_001122082.1
1118
127523
S355
A
A
Q
T
P
P
A
S
I
E
V
D
E
N
I
Chimpanzee
Pan troglodytes
XP_001168710
1118
127532
S355
A
A
Q
T
P
P
A
S
I
E
V
D
E
N
I
Rhesus Macaque
Macaca mulatta
XP_001114466
1118
127660
S355
A
A
Q
I
P
P
P
S
I
E
V
D
E
N
I
Dog
Lupus familis
XP_535474
1116
127497
S355
T
A
Q
M
P
L
P
S
V
E
I
N
E
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80U87
1080
122592
P355
P
T
Q
M
P
P
P
P
I
E
T
N
E
K
A
Rat
Rattus norvegicus
NP_001099972
1081
122532
A349
P
V
P
S
K
L
P
A
Q
M
P
P
P
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507996
1116
126304
P351
A
A
Q
V
R
P
S
P
V
A
G
N
E
N
T
Chicken
Gallus gallus
XP_413830
1116
127997
P355
V
A
P
I
K
P
S
P
T
E
V
V
E
N
E
Frog
Xenopus laevis
NP_001080551
1063
120542
S351
V
A
K
E
E
L
P
S
V
P
I
K
V
S
S
Zebra Danio
Brachydanio rerio
XP_693811
1099
124389
A348
A
S
V
C
E
E
P
A
S
A
A
Q
M
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650948
896
102648
A203
M
S
A
G
R
L
Q
A
R
L
S
S
S
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784858
1187
131804
N343
L
P
S
Q
Q
L
N
N
V
P
T
S
H
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93Y01
910
102631
S217
Y
K
S
L
E
E
S
S
L
H
M
D
Q
D
I
Baker's Yeast
Sacchar. cerevisiae
P32571
926
105173
L233
D
T
K
N
I
I
C
L
E
P
I
S
F
K
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.3
91.8
N.A.
81.8
81.9
N.A.
76.9
74.4
59.9
53.5
N.A.
31.4
N.A.
N.A.
39
Protein Similarity:
100
99.7
99.1
95.3
N.A.
88
87.7
N.A.
87
84.8
74.2
69.5
N.A.
47.7
N.A.
N.A.
56.3
P-Site Identity:
100
100
86.6
53.3
N.A.
40
0
N.A.
40
40
13.3
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
46.6
20
N.A.
60
46.6
40
26.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.3
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
50
8
0
0
0
15
22
0
15
8
0
0
8
8
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
29
0
8
0
% D
% Glu:
0
0
0
8
22
15
0
0
8
43
0
0
50
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
15
8
8
0
0
29
0
22
0
0
0
36
% I
% Lys:
0
8
15
0
15
0
0
0
0
0
0
8
0
15
8
% K
% Leu:
8
0
0
8
0
36
0
8
8
8
0
0
0
0
8
% L
% Met:
8
0
0
15
0
0
0
0
0
8
8
0
8
0
8
% M
% Asn:
0
0
0
8
0
0
8
8
0
0
0
22
0
50
0
% N
% Pro:
15
8
15
0
36
43
43
22
0
22
8
8
8
8
8
% P
% Gln:
0
0
43
8
8
0
8
0
8
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
15
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
15
15
8
0
0
22
43
8
0
8
22
8
15
8
% S
% Thr:
8
15
0
15
0
0
0
0
8
0
15
0
0
0
8
% T
% Val:
15
8
8
8
0
0
0
0
29
0
29
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _