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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBX2
All Species:
40.91
Human Site:
Y179
Identified Species:
75
UniProt:
P40425
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40425
NP_002577.2
430
45881
Y179
Y
H
S
E
L
E
K
Y
E
Q
A
C
N
E
F
Chimpanzee
Pan troglodytes
XP_001163104
443
47321
Y179
Y
H
S
E
L
E
K
Y
E
Q
A
C
N
E
F
Rhesus Macaque
Macaca mulatta
XP_001084010
407
44166
Y153
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Dog
Lupus familis
XP_850252
426
45439
Y175
Y
H
S
E
L
E
K
Y
E
Q
A
C
N
E
F
Cat
Felis silvestris
Mouse
Mus musculus
O35984
430
45791
Y179
Y
H
S
E
L
E
K
Y
E
Q
A
C
N
E
F
Rat
Rattus norvegicus
NP_001002828
430
45809
Y179
Y
H
S
E
L
E
K
Y
E
Q
A
C
N
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508896
400
44150
Y136
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Chicken
Gallus gallus
NP_001025849
433
47074
Y169
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Frog
Xenopus laevis
Q6IR52
445
49385
Y172
Y
H
A
E
L
E
K
Y
E
Q
A
C
N
E
F
Zebra Danio
Brachydanio rerio
NP_001077322
429
46552
Y167
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40427
376
41673
G126
G
P
E
K
G
G
G
G
A
A
A
A
S
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41779
338
38136
D88
A
E
G
V
A
G
P
D
K
G
G
S
L
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJ56
680
74445
I320
T
S
L
A
L
K
T
I
S
R
Q
F
R
C
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
73.7
97.2
N.A.
97.9
98.1
N.A.
65.8
77.3
71
76.2
N.A.
63.4
N.A.
48.3
N.A.
Protein Similarity:
100
97
81.6
97.4
N.A.
98.5
98.5
N.A.
74.4
83.1
77.7
84.4
N.A.
72.5
N.A.
61.1
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
20
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
0
0
8
8
85
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
77
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
77
0
77
0
0
77
0
0
0
0
77
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
77
% F
% Gly:
8
0
8
0
8
16
8
8
0
8
8
0
0
8
0
% G
% His:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
77
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
85
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
77
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% R
% Ser:
0
8
39
0
0
0
0
0
8
0
0
8
8
0
8
% S
% Thr:
8
0
31
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
77
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _